Analytical Data
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基因名
IQGAP2
- Application
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别名
IQGAP2；Ras GTPase-activating-like Protein IQGAP2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13576
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IQGAP2 is a member of the IQGAP family of proteins, which are known to regulate a variety of cellular processes, including cytoskeletal dynamics, signal transduction, and cell adhesion. Studies have shown that IQGAP2 plays a critical role in the modulation of actin filaments and microtubules, thereby influencing cell shape and motility. Unlike its closely related counterpart IQGAP1, which has been extensively studied for its involvement in cancer progression and various signaling pathways, the functional roles and mechanisms of IQGAP2 remain less understood. Preliminary research suggests that IQGAP2 may contribute to neuronal development and immune responses, indicating its potential relevance in neurological disorders and inflammatory diseases. The recombinant expression of IQGAP2 protein is crucial for elucidating its structure-function relationships and regulatory roles in biological systems. Understanding IQGAP2's interactions with other molecular players and its regulatory pathways could provide insights into its contribution to various physiological and pathological processes. Hence, the production of high-quality recombinant IQGAP2 proteins in suitable expression systems allows for comprehensive biochemical assays, structural analysis, and functional characterization, which are vital for advancing our knowledge of this protein and its potential as a therapeutic target.
