Analytical Data
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Gene name
TSPYL2
- Application
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Alternative Names
CASK interacting nucleosome assembly Protein; CDA1; Cell division autoantigen 1; Cell division autoantigen 1 nucleolar Protein; CTCL tumor antigen se20-4; CTCL-associated antigen se20-4; Cutaneous T-cell lymphoma-associated antigen se20-4; DENTT; Differentially-expressed nucleolar TGF-beta1 target Protein; HRIHFB2216; NP79; Nuclear Protein of 79 kDa; Testis-specific Y-encoded-like Protein 2; TSPX; TSPY-like Protein 2; TSPYL2; TSYL2_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H2G4
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Expression Region
1-693 aa
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AA Sequence
MDRPDEGPPA KTRRLSSSES PQRDPPPPPP PPPLLRLPLP PPQQRPRLQE ETEAAQVLAD MRGVGLGPAL PPPPPYVILE EGGIRAYFTL GAECPGWDST IESGYGEAPP PTESLEALPT PEASGGSLEI DFQVVQSSSF GGEGALETCS AVGWAPQRLV DPKSKEEAII IVEDEDEDER ESMRSSRRRR RRRRRKQRKV KRESRERNAE RMESILQALE DIQLDLEAVN IKAGKAFLRL KRKFIQMRRP FLERRDLIIQ HIPGFWVKAF LNHPRISILI NRRDEDIFRY LTNLQVQDLR HISMGYKMKL YFQTNPYFTN MVIVKEFQRN RSGRLVSHST PIRWHRGQEP QARRHGNQDA SHSFFSWFSN HSLPEADRIA EIIKNDLWVN PLRYYLRERG SRIKRKKQEM KKRKTRGRCE VVIMEDAPDY YAVEDIFSEI SDIDETIHDI KISDFMETTD YFETTDNEIT DINENICDSE NPDHNEVPNN ETTDNNESAD DHETTDNNES ADDNNENPED NNKNTDDNEE NPNNNENTYG NNFFKGGFWG SHGNNQDSSD SDNEADEASD DEDNDGNEGD NEGSDDDGNE GDNEGSDDDD RDIEYYEKVI EDFDKDQADY EDVIEIISDE SVEEEGIEEG IQQDEDIYEE GNYEEEGSED VWEEGEDSDD SDLEDVLQVP NGWANPGKRG KTG
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Molecular Weight
79.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TSPYL2, a member of the TSPY gene family, has emerged as a critical player in various biological processes, including cell proliferation, differentiation, and apoptosis. The protein is predominantly expressed in the testis and is believed to be involved in male gametogenesis, making it a vital component for fertility research. Recent studies have indicated that TSPYL2 may also have implications in cancer biology, as its expression levels have been linked to different tumor types, suggesting a potential role as a tumor suppressor or promoter depending on the context. Furthermore, TSPYL2 is thought to be associated with epigenetic regulation, influencing chromatin remodeling and gene expression. To elucidate its functional mechanisms, researchers have focused on the production and characterization of recombinant TSPYL2. This involves expressing the TSPYL2 protein in various systems, such as bacterial or mammalian cells, to study its structural properties and biological activities. Understanding the functional dynamics of TSPYL2 through recombinant protein studies could shed light on its role in development and disease, providing insights for potential therapeutic interventions. As research in this area continues to evolve, unraveling the complexities of TSPYL2 may contribute significantly to our knowledge of reproductive biology and cancer therapeutics.
