Analytical Data
-
Gene name
TSPAN17
- Application
-
Alternative Names
TSPAN17; FBXO23; TM4SF17; Tetraspanin-17; Tspan-17; F-box only Protein 23; Tetraspan Protein SB134; Transmembrane 4 superfamily member 17
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q96FV3
-
Expression Region
1-329 aa
-
AA Sequence
MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGICLAQNLVSDIKAVKANWSKWNDDFENHWLTPTISEVLSTAGPQQNSLTGAPGPAPPSRHVFFGLGGLYPEPTFKNW
-
Molecular Weight
63.1 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TSPAN17, a member of the tetraspanin family, plays a crucial role in various cellular processes, including cell adhesion, migration, and signal transduction. Research has shown that tetraspanins are integral in forming specialized membrane microdomains known as tetraspanin-enriched microdomains (TEMs), which facilitate the interaction of various cell surface proteins and contribute to the regulation of immune responses and cellular signaling pathways. Recent studies have highlighted TSPAN17's involvement in cancer progression and metastasis, suggesting that it may serve as a potential biomarker for certain cancer types. The recombinant protein of TSPAN17 allows for a more in-depth investigation into its structural characteristics and functional properties. Producing this protein in a recombinant form opens avenues for studying its interactions with other cellular proteins and its role in disease mechanisms. Furthermore, understanding TSPAN17's function may provide insights into its potential as a therapeutic target. As research continues to unveil the complexities of TSPAN17's role in cellular dynamics, the recombinant protein serves as a valuable tool for dissecting its contributions to health and disease.
