Analytical Data
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Gene name
TSKS
- Application
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Alternative Names
TSKS; STK22S1; TSKS1Testis-specific serine kinase substrate; Testis-specific kinase substrate; STK22 substrate 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UJT2
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Expression Region
1-592 aa
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AA Sequence
MASVVVKTIW QSKEIHEAGD TPTGVESCSQ LVPEAPRRVT SRAKGIPKKK KAVSFHGVEP QMSHQPMHWC LNLKRSSACT NVSLLNLAAM EPTDSTGTDS TVEDLSGQLT LAGPPASPTL PWDPDDADIT EILSGVNSGL VRAKDSITSL KEKTNRVNQH VQSLQSECSV LSENLERRRQ EAEELEGYCI QLKENCWKVT RSVEDAEIKT NVLKQNSALL EEKLRYLQQQ LQDETPRRQE AELQEPEEKQ EPEEKQEPEE KQKPEAGLSW NSLGPAATSQ GCPGPPGSPD KPSRPHGLVP AGWGMGPRAG EGPYVSEQEL QKLFTGIEEL RREVSSLTAR WHQEEGAVQE ALRLLGGLGG RVDGFLGQWE RAQREQAQTA RDLQELRGRA DELCTMVERS AVSVASLRSE LEGLGPLKPI LEEFGRQFQN SRRGPDLSMN LDRSHQGNCA RCASQGSQLS TESLQQLLDR ALTSLVDEVK QRGLTPACPS CQRLHKKILE LERQALAKHV RAEALSSTLR LAQDEALRAK NLLLTDKMKP EEKMATLDHL HLKMCSLHDH LSNLPLEGST GTMGGGSSAG TPPKQGGSAP EQ
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Molecular Weight
65.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of TSKS (testis-specific kinase 1) recombinant protein is situated at the intersection of molecular biology and reproductive health. TSKS is a serine/threonine kinase predominantly expressed in the male germline, playing a crucial role in spermatogenesis. Disruptions in its expression or function have been implicated in male infertility, making it a significant focus for researchers exploring the underlying mechanisms of reproductive disorders. The recombinant expression of TSKS allows for detailed biochemical characterization of the protein, facilitating studies on its enzymatic activity, cellular interactions, and potential downstream signaling pathways. Furthermore, understanding TSKS at a molecular level can lead to the development of novel therapeutic strategies targeting male infertility. As the global prevalence of male infertility rises, research into TSKS not only enhances our knowledge of male reproductive biology but also holds promise for innovative diagnostics and treatments, thus contributing to public health and reproductive well-being. This comprehensive examination of TSKS recombinant protein aims to unravel its multifaceted role in fertility and to inform future studies on reproductive health.
