Analytical Data
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基因名
HCRP1
- Application
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别名
HCRP1；HCRP1；Vacuolar Protein sorting-associated Protein 37A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NEZ2
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表达区间
1-397aa
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氨基酸序列
MSWLFPLTKS ASSSAAGSPG GLTSLQQQKQ RLIESLRNSH SSIAEIQKDV EYRLPFTINN LTININILLP PQFPQEKPVI SVYPPIRHHL MDKQGVYVTS PLVNNFTMHS DLGKIIQSLL DEFWKNPPVL APTSTAFPYL YSNPSGMSPY ASQGFPFLPP YPPQEANRSI TSLSVADTVS SSTTSHTTAK PAAPSFGVLS NLPLPIPTVD ASIPTSQNGF GYKMPDVPDA FPELSELSVS QLTDMNEQEE VLLEQFLTLP QLKQIITDKD DLVKSIEELA RKNLLLEPSL EAKRQTVLDK YELLTQMKST FEKKMQRQHE LSESCSASAL QARLKVAAHE AEEESDNIAE DFLEGKMEID DFLSSFMEKR TICHCRRAKE EKLQQAIAMH SQFHAPL
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HCRP1, or the Human Cardiac Repressor Protein 1, is a crucial transcriptional regulator primarily expressed in cardiac tissues. Its role has garnered substantial interest in recent years due to its implications in cardiac development and disease. Research shows that HCRP1 is involved in the modulation of various signaling pathways, which influence cardiomyocyte differentiation and cardiac hypertrophy. Dysregulation of HCRP1 expression has been linked to several cardiovascular diseases, including heart failure and arrhythmias, highlighting its potential as a therapeutic target. The recombinant protein form of HCRP1 is particularly valuable for studying its functional mechanisms, as well as for exploring its role in cellular processes and interactions with other proteins. Advances in recombinant DNA technology have facilitated the production of HCRP1, enabling in vitro functional assays and structural studies, which are essential for understanding its molecular properties and developing innovative treatments for heart-related ailments. As cardiovascular diseases remain a leading cause of morbidity and mortality worldwide, ongoing research into the HCRP1 recombinant protein promises to illuminate new pathways for intervention and may significantly contribute to improving cardiac health outcomes.
