Analytical Data
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Gene name
PSMD10
- Application
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Alternative Names
PSMD10；26S proteasome non-ATPase regulatory subunit 10
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75832
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Expression Region
1-226aa
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AA Sequence
MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG
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Molecular Weight
40.4kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SPIN3, short for SPIN (Sperm-associated antigen 3)-3, is a member of the SPIN family of proteins, which have garnered significant interest in the field of reproductive biology and cancer research. Initially identified as a sperm-associated protein, SPIN3 is believed to play a crucial role in sperm maturation and fertility. The exploration of SPIN3 has broader implications, particularly in understanding the mechanisms of gametogenesis and potential infertility issues in males. Additionally, intriguing findings suggest that SPIN3 may have links to tumorigenesis, positioning it as a potential biomarker or therapeutic target in certain cancers. Research on SPIN3 investigates its molecular structure, functional dynamics, and expression patterns in various tissues, paving the way for a better understanding of its biological significance. The interplay between SPIN3 and cellular signaling pathways is also a critical area of study, as it could unveil novel insights into both normal physiological processes and disease states. Moreover, given the increasing prevalence of infertility and cancer, the investigation of proteins like SPIN3 holds promise for developing innovative diagnostic and therapeutic strategies. As researchers delve deeper into the roles of SPIN3, the ultimate goal is to elucidate its functions and contributions to both reproductive health and oncological disorders, highlighting its potential as a focal point in translational medicine.
