Analytical Data
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基因名
TRIM29
- Application
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别名
Ataxia telangiectasia group D associated Protein; Ataxia telangiectasia group D-associated Protein; ATDC; FLJ36085; TRI29_HUMAN; TRIM 29; TRIM29; Tripartite motif containing 29; Tripartite motif containing Protein 29; Tripartite motif Protein 29; Tripartite motif Protein TRIM29; Tripartite motif-containing Protein 29
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14134
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表达区间
1-588 aa
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氨基酸序列
MEAADASRSN GSSPEARDAR SPSGPSGSLE NGTKADGKDA KTTNGHGGEA AEGKSLGSAL KPGEGRSALF AGNEWRRPII QFVESGDDKN SNYFSMDSME GKRSPYAGLQ LGAAKKPPVT FAEKGELRKS IFSESRKPTV SIMEPGETRR NSYPRADTGL FSRSKSGSEE VLCDSCIGNK QKAVKSCLVC QASFCELHLK PHLEGAAFRD HQLLEPIRDF EARKCPVHGK TMELFCQTDQ TCICYLCMFQ EHKNHSTVTV EEAKAEKETE LSLQKEQLQL KIIEIEDEAE KWQKEKDRIK SFTTNEKAIL EQNFRDLVRD LEKQKEEVRA ALEQREQDAV DQVKVIMDAL DERAKVLHED KQTREQLHSI SDSVLFLQEF GALMSNYSLP PPLPTYHVLL EGEGLGQSLG NFKDDLLNVC MRHVEKMCKA DLSRNFIERN HMENGGDHRY VNNYTNSFGG EWSAPDTMKR YSMYLTPKGG VRTSYQPSSP GRFTKETTQK NFNNLYGTKG NYTSRVWEYS SSIQNSDNDL PVVQGSSSFS LKGYPSLMRS QSPKAQPQTW KSGKQTMLSH YRPFYVNKGN GIGSNEAP
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分子量
65.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TRIM29, also known as ret finger protein 3 (RFP3), is a member of the tripartite motif (TRIM) family of proteins, which are known to play crucial roles in various cellular processes, including immunity, cell proliferation, and differentiation. The study of TRIM29 has gained attention due to its involvement in different types of cancers and inflammatory diseases. It has been reported that TRIM29 functions as a tumor suppressor in some contexts while potentially behaving as an oncogene in others, depending on the cellular environment and specific post-translational modifications. This dual role complicates our understanding of its biological functions and mechanisms. Furthermore, TRIM29 is implicated in the regulation of epithelial to mesenchymal transition (EMT), a key process in tumor metastasis. Research has shown that manipulating TRIM29 expression can influence cell migration and invasion, highlighting its potential as a therapeutic target. The use of recombinant TRIM29 protein in studies allows for deeper exploration of its functional role and interactions at the molecular level. As such, the characterization of TRIM29 and its recombinant forms offers valuable insights into its biological roles and mechanisms, which could pave the way for novel therapeutic approaches in cancer and inflammation-related disorders. Understanding the precise biological activities and regulatory mechanisms of TRIM29 through recombinant protein studies is essential for developing strategies aimed at modulating its function in disease contexts.
