Analytical Data
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Gene name
ZNF364
- Application
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Alternative Names
E3 ubiquitin-Protein ligase RNF115. EC:2.3.2.27. RING finger Protein 115. RING-type E3 ubiquitin transferase RNF115. Rab7-interacting RING finger Protein. Rabring 7. Zinc finger Protein 364
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y4L5
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Expression Region
2-305 aa
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AA Sequence
AEASAAGAD AGSAVAAHRF FCHFCKGEVN PKLPEYICPR CDSGFIEEVT DDSSFLGGGG SRTDNSTATH FAELWDHLDH TMFLQDFRPF LSSNPLDQDN RANERGHQTH TDFWGPSRPP RLPMTRRYRS RGSTRPDRSP AIEGIIQQIF AGFFANSAIP GSPHPFSWSG MLHSNPGDYA WGQTGLDAIV TQLLGQLENT GPPPADKEKI TSLPTVTVTQ EQVNTGLECP VCKEDYTVEE KVRQLPCNHF FHSSCIVPWL ELHDTCPVCR KSLNGEDSTR QTQSSEASAS NRFSNDSQLH DRWTF
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Molecular Weight
33.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF364, a member of the zinc finger protein family, has garnered attention due to its potential roles in gene regulation, cellular differentiation, and development. These proteins are characterized by the presence of zinc finger motifs, which facilitate DNA binding and modulation of gene expression. Research has indicated that ZNF364 may be implicated in various biological processes related to developmental disorders and certain cancers, making it a significant target for study. The understanding of ZNF364's structure and function is essential, as it could reveal insights into its mechanisms of action in health and disease. Recent advances in recombinant protein technology have enabled the production of ZNF364 in a laboratory setting, allowing researchers to investigate its biochemical properties, interaction networks, and functional roles in cellular pathways. Moreover, studying ZNF364 through recombinant methods can lead to the development of potential therapeutic strategies, including targeted gene therapies or novel drug designs. Overall, the exploration of ZNF364 as a recombinant protein represents a promising avenue for uncovering its biological significance and therapeutic potential.











