Analytical Data
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Gene name
SNAG1
- Application
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Alternative Names
SNAG1；SH3PXD3B；Sorting nexin-18
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96RF0
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Expression Region
1-628aa
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AA Sequence
MALRARALYD FRSENPGEIS LREHEVLSLC SEQDIEGWLE GVNSRGDRGL FPASYVQVIR APEPGPAGDG GPGAPARYAN VPPGGFEPLP VAPPASFKPP PDAFQALLQP QQAPPPSTFQ PPGAGFPYGG GALQPSPQQL YGGYQASQGS DDDWDDEWDD SSTVADEPGA LGSGAYPDLD GSSSAGVGAA GRYRLSTRSD LSLGSRGGSV PPQHHPSGPK SSATVSRNLN RFSTFVKSGG EAFVLGEASG FVKDGDKLCV VLGPYGPEWQ ENPYPFQCTI DDPTKQTKFK GMKSYISYKL VPTHTQVPVH RRYKHFDWLY ARLAEKFPVI SVPHLPEKQA TGRFEEDFIS KRRKGLIWWM NHMASHPVLA QCDVFQHFLT CPSSTDEKAW KQGKRKAEKD EMVGANFFLT LSTPPAAALD LQEVESKIDG FKCFTKKMDD SALQLNHTAN EFARKQVTGF KKEYQKVGQS FRGLSQAFEL DQQAFSVGLN QAIAFTGDAY DAIGELFAEQ PRQDLDPVMD LLALYQGHLA NFPDIIHVQK GKAWPLEQVI WSVLCRLKGA TLTAVPLWVS ESYSTGEEAS RDVDAWVFSL ECKLDCSTGS FLLEYLALGN EYSFSKVQRV PLMTVLSF
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNAG1, a member of the SNAG (suppressor of nuclear hormone receptor signaling) protein family, has garnered significant attention in recent years due to its potential roles in cell differentiation, development, and oncogenesis. This protein is characterized by its SNAG domain, which facilitates transcriptional repression and interacts with various nuclear receptors. Research indicates that SNAG1 is involved in the regulation of genes associated with stem cell pluripotency and differentiation, suggesting a crucial function in maintaining the balance between stemness and lineage commitment. Moreover, abnormalities in SNAG1 expression have been linked to various cancers, highlighting its significance in tumorigenesis. The investigation of SNAG1 as a recombinant protein has provided insights into its structural and functional properties, enabling the elucidation of its mechanisms of action at the molecular level. Recombinant techniques allow for the production of high-purity SNAG1, which is essential for functional assays and structural studies. Furthermore, the functional characterization of SNAG1 can pave the way for potential therapeutic interventions in diseases where its dysregulation is implicated. Understanding the precise role of SNAG1 in cellular processes not only enhances our comprehension of fundamental biological mechanisms but also contributes to the development of novel biomarkers and therapeutic targets in regenerative medicine and cancer treatment. Thus, SNAG1 represents a promising candidate for further investigation, underscoring the importance of recombinant protein studies in advancing biomedical research.
