Analytical Data
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Gene name
THSD4
- Application
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Alternative Names
THSD4; UNQ9334/PRO34005; Thrombospondin type-1 domain-containing Protein 4; A disintegrin and metalloProteinase with thrombospondin motifs-like Protein 6; ADAMTS-like Protein 6; ADAMTSL-6
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6ZMP0
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Expression Region
1-490 aa
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AA Sequence
MYKSNNYLALRSRSGRSIINGNWAIDRPGKYEGGGTMFTYKRPNEISSTAGESFLAEGPTNEILDVYMIHQQPNPGVHYEYVIMGTNAISPQVPPHRRPGEPFNGQMVTEGRSQEEGEQKGRNEEKEDLRGEAPEMFTSESAQTFPVRHPDRFSPHRPDNLVPPAPQPPRRSRDHNWKQLGTTECSTTCGKGSQYPIFRCVHRSTHEEAPESYCDSSMKPTPEEEPCNIFPCPAFWDIGEWSECSKTCGLGMQHRQVLCRQVYANRSLTVQPYRCQHLEKPETTSTCQLKICSEWQIRTDWTSCSVPCGVGQRTRDVKCVSNIGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSERCSAECGAGVRTRSVVCMTNHVSSLPLEGCGNNRPAEATPCDNGPCTGKVEWFAGSWSQCSIECGSGTQQREVICVRKNADTFEVLDPSECSFLEKPPSQQSCHLKPCGAKWFSTEWSMSLQRAMLTRPS
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Molecular Weight
81.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
THSD4 (Thrombospondin Type 1 Domain Containing 4) is a member of the thrombospondin family of proteins, which play essential roles in cell adhesion, migration, and the modulation of various signaling pathways. Research into THSD4 has gained attention due to its emerging role in developmental processes and pathological conditions, including cancer and cardiovascular diseases. The expression of THSD4 has been linked to angiogenesis and the organization of the extracellular matrix, suggesting its potential involvement in tumor progression and metastasis. In addition, studies have indicated that THSD4 may interact with various growth factors and receptors, raising questions about its precise function in cellular contexts. The investigation of THSD4 recombinant protein has become crucial for elucidating its biological roles and potential as a therapeutic target. Utilizing techniques such as recombinant DNA technology allows for the production of THSD4 in controlled environments, facilitating in-depth studies of its structure-function relationships. Understanding the mechanisms by which THSD4 influences cell behavior could yield insights into novel strategies for disease intervention and highlight its potential as a biomarker for certain conditions. Overall, the characterization of THSD4 and its recombinant protein holds promise for advancing our knowledge of its roles in health and disease.
