Analytical Data
-
基因名
ZDHHC19
- Application
-
别名
ZDHHC19; Palmitoyltransferase ZDHHC19; Zinc finger DHHC domain-containing Protein 19; DHHC-19
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q8WVZ1
-
表达区间
1-243 aa
-
氨基酸序列
MTLLTDATPLVKEPHPLPLVPRPWFLPSLFAAFNVVLLVFFSGLFFAFPLVSLNFSDPGILHQGSAEQGPLTVHVVWVNHGAFRLQWCPKCCFHRPPRTYHCPWCNICVEVSAPLPVHQPSPHIWLGPGASLIQGPGLGVKLFSGLLKAKGGSNSQPPLVTHVFSTCTCPGRLAVACRGADMHRASASVLGWVRPGEERQPSVPPLGSLTRDTQAPQAGCPPGLGGLACPRLGVQVGGSPGSE
-
分子量
52.2 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZDHHC19, a member of the ZDHHC-containing palmitoyl acyltransferase family, plays a crucial role in post-translational modification processes, specifically in the palmitoylation of proteins. This modification is essential for regulating the stability, localization, and function of various target proteins, impacting numerous cellular processes. Studies have indicated that ZDHHC19 is involved in several important physiological functions, including neuronal signaling, metabolism, and cell membrane dynamics. Dysregulation of ZDHHC19 activity has been linked to various diseases, including neurodegenerative disorders and certain cancers. Given its significance, the recombinant expression of ZDHHC19 has become a critical area of research, facilitating the study of its enzymatic mechanisms and substrate specificity. The production of ZDHHC19 as a recombinant protein allows for detailed biochemical analyses and structure-function studies, crucial for understanding its role in cellular signaling pathways. Moreover, insights gained from ZDHHC19 research could potentially lead to therapeutic interventions, targeting the palmitoylation process to correct dysregulated pathways associated with disease. Hence, the investigation of ZDHHC19 not only enhances our understanding of cellular functions but also paves the way for innovative strategies in disease treatment and prevention.
