Analytical Data
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基因名
TAF13
- Application
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别名
TAF13;TAF2K;TAFII18;Transcription initiation factor TFIID subunit 13
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15543
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表达区间
1-124aa
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氨基酸序列
MADEEEDPTF EEENEEIGGG AEGGQGKRKR LFSKELRCMM YGFGDDQNPY TESVDILEDL VIEFITEMTH KAMSIGRQGR VQVEDIVFLI RKDPRKFARV KDLLTMNEEL KRARKAFDEA NYGS
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TAF13, a crucial component of the Transcription Factor IID (TFIID) complex, plays a significant role in the regulation of gene expression by bridging the interactions between general transcription factors and RNA polymerase II. Recent studies have highlighted the importance of TAF13 in various cellular processes, including cell proliferation, differentiation, and response to stress, indicating its fundamental role in maintaining cellular homeostasis. Additionally, mutations or dysregulation of TAF13 have been implicated in several diseases, including cancers, which further underscores its potential as a therapeutic target. The recombinant expression of TAF13 has facilitated detailed investigations into its functional mechanisms, interactions with other transcriptional components, and its impact on transcriptional regulation. Understanding the structural and biochemical properties of TAF13 is paramount for elucidating its precise role in transcriptional regulation and its broader implications in health and disease. Therefore, the research focused on TAF13 recombinant protein is pivotal in both basic biology and potential clinical applications, contributing to the broader understanding of transcriptional processes and the development of novel therapeutic strategies.












