Analytical Data
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Gene name
SRPX
- Application
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Alternative Names
SRPX; ETX1; Sushi repeat-containing protein SRPX
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P78539
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Expression Region
31-464aa
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AA Sequence
FPGSGDSPLEDDEVGYSHPRYKDTPWCSPIKVKYGDVYCRAPQGGYYKTALGTRCDIRCQ KGYELHGSSLLICQSNKRWSDKVICKQKRCPTLAMPANGGFKCVDGAYFNSRCEYYCSPG YTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLTVRVSWETPEGRD TADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVRVKRCGKLNAPEN GYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMNVNVGVRTAA ALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRI GAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERYVSLVMPVALFNLIDTFPLRKE EMVLQAEMSQTCNT
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Molecular Weight
51.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The SRPX (Sushi-repeat-containing protein X) is a protein implicated in various biological processes, particularly in the development and function of the central nervous system. Its role in neural connectivity has garnered attention due to its association with neurological disorders, including speech and language impairments, such as those found in individuals with a specific form of mental retardation. The significance of SRPX lies in its structural composition, which includes sushi repeats, thought to facilitate protein-protein interactions, critical for cellular signaling and adhesion. Research has shown that altered expression or mutations in SRPX can disrupt normal neural development, leading to cognitive and communicative challenges. As a result, SRPX has become a target for investigation to better understand its mechanisms and therapeutic potential in treating related disorders. Efforts to characterize recombinant forms of SRPX aim to elucidate its functional roles and interactions within neuronal networks, thereby contributing to the broader understanding of neurodevelopmental pathways and potential interventions for associated disorders. This ongoing research not only highlights the importance of SRPX in fundamental neurobiology but also illustrates the potential for SRPX-targeted therapies in addressing significant health challenges.
