Analytical Data
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基因名
SRPX
- Application
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别名
SRPX; ETX1; Sushi repeat-containing protein SRPX
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P78539
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表达区间
31-464aa
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氨基酸序列
FPGSGDSPLEDDEVGYSHPRYKDTPWCSPIKVKYGDVYCRAPQGGYYKTALGTRCDIRCQ KGYELHGSSLLICQSNKRWSDKVICKQKRCPTLAMPANGGFKCVDGAYFNSRCEYYCSPG YTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLTVRVSWETPEGRD TADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVRVKRCGKLNAPEN GYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMNVNVGVRTAA ALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRI GAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERYVSLVMPVALFNLIDTFPLRKE EMVLQAEMSQTCNT
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分子量
51.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The SRPX (Sushi-repeat-containing protein X) is a protein implicated in various biological processes, particularly in the development and function of the central nervous system. Its role in neural connectivity has garnered attention due to its association with neurological disorders, including speech and language impairments, such as those found in individuals with a specific form of mental retardation. The significance of SRPX lies in its structural composition, which includes sushi repeats, thought to facilitate protein-protein interactions, critical for cellular signaling and adhesion. Research has shown that altered expression or mutations in SRPX can disrupt normal neural development, leading to cognitive and communicative challenges. As a result, SRPX has become a target for investigation to better understand its mechanisms and therapeutic potential in treating related disorders. Efforts to characterize recombinant forms of SRPX aim to elucidate its functional roles and interactions within neuronal networks, thereby contributing to the broader understanding of neurodevelopmental pathways and potential interventions for associated disorders. This ongoing research not only highlights the importance of SRPX in fundamental neurobiology but also illustrates the potential for SRPX-targeted therapies in addressing significant health challenges.
