Analytical Data
-
基因名
MAPKAP1
- Application
-
别名
MAPKAP1；MIP1；SIN1；Target of rapamycin complex 2 subunit MAPKAP1
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9BPZ7
-
表达区间
2-522aa
-
氨基酸序列
AFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGETQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQELKSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVYLPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRKGSQKVSGPQYRLEKQSEPNVAVDLDSTLESQSAWEFCLVRENSSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
-
分子量
65.9 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MAPKAP1, or Mitogen-Activated Protein Kinase-Associated Protein 1, plays a crucial role in various cellular processes, including cell growth, differentiation, and response to stress signals. It is a serine/threonine protein kinase that is primarily activated by the MAPK pathway, specifically by p38 MAPK, which is involved in inflammatory responses and cellular adaptation to stress. Research on MAPKAP1 has gained prominence due to its implications in various diseases, including cancer, cardiovascular disorders, and neurodegenerative diseases. Given its involvement in key signaling pathways, MAPKAP1 may serve as a potential therapeutic target for modulating these diseases. The generation of recombinant MAPKAP1 protein enables researchers to study its structure, function, and interactions with other cellular components in detail. Moreover, investigating the effects of specific mutations or post-translational modifications in MAPKAP1 can shed light on its role in disease mechanisms. Consequently, understanding the regulatory mechanisms governing MAPKAP1 activity could provide insights into novel treatment strategies and biomarker development.
