Analytical Data
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Gene name
MAPKAP1
- Application
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Alternative Names
MAPKAP1；MIP1；SIN1；Target of rapamycin complex 2 subunit MAPKAP1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BPZ7
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Expression Region
2-522aa
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AA Sequence
AFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGETQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQELKSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVYLPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRKGSQKVSGPQYRLEKQSEPNVAVDLDSTLESQSAWEFCLVRENSSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
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Molecular Weight
65.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MAPKAP1, or Mitogen-Activated Protein Kinase-Associated Protein 1, plays a crucial role in various cellular processes, including cell growth, differentiation, and response to stress signals. It is a serine/threonine protein kinase that is primarily activated by the MAPK pathway, specifically by p38 MAPK, which is involved in inflammatory responses and cellular adaptation to stress. Research on MAPKAP1 has gained prominence due to its implications in various diseases, including cancer, cardiovascular disorders, and neurodegenerative diseases. Given its involvement in key signaling pathways, MAPKAP1 may serve as a potential therapeutic target for modulating these diseases. The generation of recombinant MAPKAP1 protein enables researchers to study its structure, function, and interactions with other cellular components in detail. Moreover, investigating the effects of specific mutations or post-translational modifications in MAPKAP1 can shed light on its role in disease mechanisms. Consequently, understanding the regulatory mechanisms governing MAPKAP1 activity could provide insights into novel treatment strategies and biomarker development.
