Analytical Data
-
基因名
CUL7
- Application
-
别名
MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVG
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q14999
-
表达区间
1-100aa
-
氨基酸序列
MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVG
-
分子量
36.63 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CUL7 (Cullin-7) is a member of the cullin family of proteins that plays a crucial role in the ubiquitin-proteasome system, which regulates protein degradation and cellular processes. Dysregulation of CUL7 has been implicated in various diseases, including cancer and genetic disorders. Research into CUL7 recombinant proteins has gained traction due to their potential to uncover the mechanisms underlying these conditions. The study of CUL7's structure and function, particularly through the generation of recombinant versions of the protein, allows scientists to explore its interactions with substrates and other components of the E3 ubiquitin ligase complex. Moreover, as mutations in the CUL7 gene can lead to disorders like 3-M syndrome, understanding its biochemical pathways may provide insights for therapeutic strategies. Recombinant CUL7 proteins can be utilized in biochemical assays to screen for small molecules that modulate its activity, offering prospects for drug development. Overall, the investigation of CUL7 recombinant proteins serves as a vital tool in elucidating the complexities of cell regulation and disease pathology, making it a significant focus of modern biomedical research.
