Cat: PA1000-7684

Recombinant Human ABCA13 Protein,His

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Analytical Data

  • Gene name

    ABCA13

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ABCA13;ATP-binding cassette sub-family A member 13

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q86UQ4

  • Expression Region

    全长

  • AA Sequence

    full

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ABCA13 is a member of the ATP-binding cassette (ABC) transporter family, which plays a crucial role in the transport of various molecules across cellular membranes. The study of ABCA13 is particularly important due to its potential implications in lipid metabolism, neurological function, and the pathogenesis of various diseases, including cancer and neurodegenerative disorders. Research has indicated that ABCA13 may be involved in the efflux of lipids and other metabolites, influencing cellular homeostasis and signaling pathways. Additionally, genetic variations in ABCA13 have been associated with altered susceptibility to certain diseases, highlighting its relevance in medical genetics and therapeutic research. Recombinant protein studies of ABCA13 enable researchers to investigate its biochemical properties and functional mechanisms, providing insights into its role in health and disease. By analyzing the structure and function of ABCA13 through various experimental approaches, including in vitro assays and cellular models, scientists aim to uncover the molecular underpinnings of its role in transporting substrates and its impact on cellular physiology. Understanding ABCA13 not only contributes to our knowledge of ABC transporters but also paves the way for developing targeted therapies that address its involvement in disease processes. Consequently, the investigation of ABCA13 recombinant protein serves as a promising avenue for advancing our understanding of complex biological systems and their implications in human health.

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