Analytical Data
-
Gene name
CSPG6
- Application
-
Alternative Names
BAM; Bamacan; Basement membrane associated chondroitin proteoglycan; Basement membrane-associated chondroitin proteoglycan; BMH; CDLS3; chondroitin sulfate proteoglycan 6 (bamacan); Chondroitin sulfate proteoglycan 6; Chromosome associated polypeptide; Chromosome-associated polypeptide; CSPG 6; CSPG6; hCAP
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9UQE7
-
Expression Region
711-810aa
-
AA Sequence
IDQLMNQMQQIETQQRKFKASRDSILSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDALNDEIRQLQQE
-
Molecular Weight
36.63 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CSPG6, also known as chondroitin sulfate proteoglycan 6, is a member of the proteoglycan family known to play crucial roles in cell signaling, development, and tissue repair. The study of CSPG6 has gained significant interest due to its involvement in various pathological conditions, including cancer and neurodegenerative diseases. It is characterized by its unique structure comprising a core protein and glycosaminoglycan (GAG) chains that mediate interactions with other extracellular matrix components and receptors on cell surfaces. Research has shown that CSPG6 influences cellular behavior, such as proliferation, migration, and differentiation, through its interactions with growth factors and adhesive proteins. Furthermore, its expression patterns vary across different tissues and developmental stages, suggesting it may have context-dependent functions. As a result, recombinant CSPG6 proteins are valuable tools for investigating its biological functions and mechanisms in both normal and disease states. Advances in recombinant DNA technology have facilitated the production of purified CSPG6 proteins, allowing for in-depth studies of its roles in cellular environments. Understanding CSPG6's contributions to cellular processes can potentially uncover novel therapeutic targets for diseases where its dysregulation plays a pivotal role. Thus, the exploration of CSPG6 through recombinant protein technology not only enhances the fundamental understanding of this proteoglycan but also paves the way for innovative strategies in disease treatment and prevention.
