Analytical Data
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Gene name
NUP188
- Application
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Alternative Names
NUP188；KIAA0169；Nucleoporin NUP188
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5SRE5
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Expression Region
全长
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AA Sequence
full
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NUP188, a member of the nucleoporin protein family, plays a crucial role in the structure and function of the nuclear pore complex (NPC), which is essential for the transport of molecules between the nucleus and the cytoplasm. Recent studies have revealed that NUP188 is involved in various cellular processes, including gene expression regulation, cell cycle progression, and response to stress. Alterations in NUP188 expression or function have been implicated in several diseases, including cancer and neurodegenerative disorders. The study of recombinant NUP188 protein has gained importance as researchers aim to understand its biochemical properties and interactions with other nucleoporins as well as nuclear transport receptors. By producing recombinant NUP188, scientists can investigate its role in nuclear transport mechanisms and its potential as a therapeutic target. Furthermore, understanding the structure and function of NUP188 may offer insights into the intricate workings of the NPC and its involvement in cellular homeostasis. Enhanced knowledge of NUP188 and its pathways could pave the way for novel approaches to treat diseases linked to nuclear transport dysfunction. Thus, the exploration of recombinant NUP188 protein not only sheds light on fundamental cellular processes but also holds promise for biomedical applications in the context of disease intervention.
