Analytical Data
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基因名
OFCC1
- Application
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别名
OFCC1；MRDS1；Orofacial cleft 1 candidate gene 1 Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IZS5
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表达区间
3-231aa
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氨基酸序列
REKFQQKALKQTKQKKSKSAEFLMVKEDREATEGTGNPAFNMSSPDLSACQTAEKKVIRHDMPDRTLAAHQQKFRLPASAEPKGNEYGRNYFDPLMDEEINPRQCATEVSREDDDRIFYNRLTKLFDESRQGEPQDESGREETLNSEAPGSSNKSHEIHKEASEATTAHLEEFQRSQKTIILLGSSPLEQEIRSTSLHCMEDEMSHPWILLLKVTAVIRSRRYYREQRF
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分子量
42.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
OFCC1, or Oligophrenin-1 Coding Gene, is a crucial gene associated with intellectual disabilities and cognitive functions. Research into OFCC1 has gained momentum due to its role in various cellular processes, including neuronal development and synaptic plasticity. Mutations or aberrations in this gene have been linked to syndromic forms of intellectual disability, particularly in cases of intellectual disorders where cognitive decline is a significant concern. Understanding OFCC1's function at a molecular level is essential for elucidating the underlying mechanisms of these disorders, potentially paving the way for targeted therapeutic strategies. Recent studies involving OFCC1 recombinant proteins have focused on elucidating its interactions with other proteins, signaling pathways, and its impact on neurodevelopment. The characterization of OFCC1's structure and function through recombinant protein techniques holds promise for identifying novel biomarkers and developing innovative treatments for related cognitive impairments. Overall, continued investigation into OFCC1 not only enhances our understanding of developmental biology but also highlights its significance in neurodevelopmental diseases, making it a compelling target for both basic and applied research in medical science.
