Analytical Data
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Gene name
OFCC1
- Application
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Alternative Names
OFCC1；MRDS1；Orofacial cleft 1 candidate gene 1 Protein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IZS5
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Expression Region
3-231aa
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AA Sequence
REKFQQKALKQTKQKKSKSAEFLMVKEDREATEGTGNPAFNMSSPDLSACQTAEKKVIRHDMPDRTLAAHQQKFRLPASAEPKGNEYGRNYFDPLMDEEINPRQCATEVSREDDDRIFYNRLTKLFDESRQGEPQDESGREETLNSEAPGSSNKSHEIHKEASEATTAHLEEFQRSQKTIILLGSSPLEQEIRSTSLHCMEDEMSHPWILLLKVTAVIRSRRYYREQRF
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Molecular Weight
42.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
OFCC1, or Oligophrenin-1 Coding Gene, is a crucial gene associated with intellectual disabilities and cognitive functions. Research into OFCC1 has gained momentum due to its role in various cellular processes, including neuronal development and synaptic plasticity. Mutations or aberrations in this gene have been linked to syndromic forms of intellectual disability, particularly in cases of intellectual disorders where cognitive decline is a significant concern. Understanding OFCC1's function at a molecular level is essential for elucidating the underlying mechanisms of these disorders, potentially paving the way for targeted therapeutic strategies. Recent studies involving OFCC1 recombinant proteins have focused on elucidating its interactions with other proteins, signaling pathways, and its impact on neurodevelopment. The characterization of OFCC1's structure and function through recombinant protein techniques holds promise for identifying novel biomarkers and developing innovative treatments for related cognitive impairments. Overall, continued investigation into OFCC1 not only enhances our understanding of developmental biology but also highlights its significance in neurodevelopmental diseases, making it a compelling target for both basic and applied research in medical science.
