Analytical Data
-
基因名
CPNE8
- Application
-
别名
Copine 8; Copine VIII; Copine-8; CPNE8; CPNE8_HUMAN; MGC129645; MGC129646
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q86YQ8
-
表达区间
1-564aa
-
氨基酸序列
MDSRYNSTAGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSPHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI
-
分子量
88.44 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CPNE8, or Copine 8, is a member of the copine family of proteins characterized by the presence of C2 and ankyrin repeat domains, which play crucial roles in cellular processes such as membrane trafficking, signal transduction, and cell adhesion. Recent studies have suggested that CPNE8 is involved in various physiological and pathological conditions, including cancer progression and neurodegenerative diseases. The protein's ability to bind calcium ions and interact with phospholipid membranes highlights its potential as a regulator in signaling pathways. Understanding CPNE8's structural and functional properties through recombinant protein studies is essential in elucidating its role in cellular mechanisms. Recombinant CPNE8 can be produced in various expression systems, allowing for detailed biochemical and biophysical characterization. This research aims to uncover the protein's interaction partners and its specific functions within cellular contexts, providing insights into its contribution to diseases and opening avenues for therapeutic interventions. The demand for targeted protein studies, particularly regarding CPNE8's implications in disease, underscores the importance of developing reliable methods for its expression and purification. Exploring CPNE8 at the molecular level may reveal novel targets for drug design and therapeutic strategies, highlighting the significance of this research in the broader landscape of molecular biology and medicine.
