Analytical Data
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Gene name
CLPTM1
- Application
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Alternative Names
CLPTM1; Cleft lip and palate transmembrane protein 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O96005
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Expression Region
1-669aa
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AA Sequence
MAAAQEADGARSAVVAAGGGSSGQVTSNGSIGRDPPAETQPQNPPAQPAPNAWQVIKGVLFRIFIIWAISSWFRRGPAPQDQAGPGGAPRVASRNLFPKDTLMNLHVYISEHEHFTDFNATSALFWEQHDLVYGDWTSGENSDGCYEHFAELDIPQSVQQNGSIYIHVYFTKSGFHPDPRQKALYRRLATVHMSRMINKYKRRRFQKTKNLLTGETEADPEMIKRAEDYGPVEVISHWHPNITINIVDDHTPWVKGSVPPPLDQYVKFDAVSGDYYPIIYFNDYWNLQKDYYPINESLASLPLRVSFCPLSLWRWQLYAAQSTKSPWNFLGDELYEQSDEEQDSVKVALLETNPYLLALTIIVSIVHSVFEFLAFKNDIQFWNSRQSLEGLSVRSVFFGVFQSFVVLLYILDNETNFVVQVSVFIGVLIDLWKITKVMDVRLDREHRVAGIFPRLSFKDKSTYIESSTKVYDDMAFRYLSWILFPLLGCYAVYGLLYLEHKGWYSWVLSMLYGFLLTFGFITMTPQLFINYKLKSVAHLPWRMLTYKALNTFIDDLFAFVIKMPVMYRIGCLRDDVVFFIYLYQRWIYRVDPTRVNEFGMSGEDPTAAAPVAEVPTAAGALTPTPAPTTTTATREEASTSLPTKPTQGASSASEPQEAPPKPAEDKKKD
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Molecular Weight
102.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CLPTM1 (Cleft Lip and Palate Transmembrane Protein 1) is a gene implicated in various cellular processes, including cellular signaling, apoptosis, and tumorigenesis. Its overexpression has been associated with several types of cancer, making it a significant focus of oncological research. Studies have demonstrated that CLPTM1 may play a critical role in the regulation of cell proliferation and survival in cancerous tissues, particularly in lung and breast cancer. The protein is thought to interact with other pathways that control cell growth, providing a potential target for therapeutic interventions. Given its involvement in malignancies, researchers have been exploring the recombinant expression of CLPTM1 to better understand its structure and function. This approach allows for the generation of large quantities of the protein, facilitating detailed biochemical and biophysical characterizations, as well as investigations into its interactions with other cellular components. Ultimately, elucidating the role of CLPTM1 in cancer biology may provide insights into novel treatment strategies and enhance our understanding of the molecular mechanisms underlying tumor development. The study of recombinant CLPTM1 could pave the way for developing targeted therapies that exploit its pathways, potentially leading to more effective cancer treatment modalities.
