Analytical Data
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基因名
SERINC1
- Application
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别名
1500011D18Rik; AI315070; AIGP 2; KIAA1253; LRRGT00191; mKIAA1253; SERC1_HUMAN; SERINC1; Serine incorporator 1; TDE1L; TDE2; TMS 2; Tms2; Tumor differentially expressed 1 protein like ; Tumor differentially expressed protein 1-like; Tumor differentially expressed protein 2; UNQ396/PRO732
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NRX5
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表达区间
1-453 aa
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氨基酸序列
MGSVLGLCSMASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFAAAIAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNMLLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTTSTVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD
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分子量
76.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SERINC1, a member of the SERINC family of proteins, has garnered significant attention in recent years due to its involvement in various cellular processes and its potential implications in virology and immunology. Originally identified for its role in modulating the immune response, SERINC1 has been shown to impact the incorporation of lipids into membranes and influence viral entry and replication. Particularly, it has been highlighted for its ability to restrict the infectivity of certain enveloped viruses, including HIV-1, by enhancing the incorporation of host cell-derived lipids into viral particles. This unique function positions SERINC1 as an important player in the host's antiviral defense mechanisms. Research into the recombinant expression of SERINC1 aims to elucidate its structure-function relationships and facilitate the development of novel antiviral strategies. Understanding SERINC1’s interactions at the molecular level can offer insights into potential therapeutic targets in viral infections and enhance the knowledge of lipid-based modulation of viral pathogenesis. The recombinant protein studies also provide a platform for exploring the protein's role in cellular signaling pathways, membrane dynamics, and overall cellular physiology, potentially revealing broader implications for understanding cellular responses to pathogenic challenges.
