Analytical Data
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Gene name
CDX4
- Application
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Alternative Names
Caudal-type homeobox Protein 4; CDX4; CDX4_HUMAN; Homeobox Protein CDX-4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O14627
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Expression Region
1-284aa
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AA Sequence
MYGSCLLEKE AGMYPGTLMS PGGDGTAGTG GTGGGGSPMP ASNFAAAPAF SHYMGYPHMP SMDPHWPSLG VWGSPYSPPR EDWSVYPGPS STMGTVPVND VTSSPAAFCS TDYSNLGPVG GGTSGSSLPG QAGGSLVPTD AGAAKASSPS RSRHSPYAWM RKTVQVTGKT RTKEKYRVVY TDHQRLELEK EFHCNRYITI QRKSELAVNL GLSERQVKIW FQNRRAKERK MIKKKISQFE NSGGSVQSDS DSISPGELPN TFFTTPSAVR GFQPIEIQQV IVSE
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Molecular Weight
30.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of CDX4 recombinant protein is rooted in its significance in developmental biology and embryogenesis. CDX4 is a member of the caudal-related homeobox (CDX) gene family, which plays a crucial role in the regulation of anterior-posterior axis formation during early development. Research has shown that CDX4 is essential for maintaining the pluripotency of embryonic stem cells and influences the differentiation process into various cell lineages, particularly in the formation of the endoderm and mesoderm. Furthermore, aberrations in CDX4 expression have been linked to developmental disorders and certain types of cancers, highlighting its potential as a biomarker for disease diagnosis and a target for therapeutic interventions. The recombinant form of CDX4 allows for detailed functional studies and interactions with other developmental proteins, offering insights into its mechanisms of action. Scientists utilize recombinant proteins to elucidate the pathways involved in cell differentiation and to explore their implications in regenerative medicine and tissue engineering. The ongoing research into CDX4 thus not only enhances our understanding of fundamental biological processes but also paves the way for innovative approaches in medical applications.
