Analytical Data
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Gene name
CCDC93
- Application
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Alternative Names
CCDC93Coiled-coil domain-containing Protein 93
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q567U6
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Expression Region
1-631aa
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AA Sequence
MGLPRGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPCRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNEMLLSKVKAKAS
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Molecular Weight
99.5 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC93 (coiled-coil domain containing 93) is a protein implicated in various cellular processes, particularly in ciliogenesis and cell signaling. Research has shown that CCDC93 plays a crucial role in the formation and maintenance of centrioles, essential structures for proper cell division and organization of cilia. Defects in CCDC93 have been linked to ciliopathy disorders, which can result in developmental abnormalities and dysfunctions in various organ systems. Due to its significant role in these biological processes, the study of recombinant CCDC93 protein has become a focal point for understanding its functional mechanisms and interactions within the cell. By producing recombinant CCDC93, researchers aim to investigate its structural properties, binding partners, and molecular pathways it influences. Such studies not only contribute to a deeper understanding of the molecular underpinnings of ciliogenesis but also have implications for developing therapeutic strategies for ciliopathies and related diseases. Furthermore, expressing CCDC93 in a controlled environment allows for detailed functional assays, providing insights into how alterations in this protein can affect cellular behavior and contribute to disease pathology. The comprehensive study of CCDC93 thus has the potential to unveil new avenues for intervention in genetic disorders linked to disruptions in cellular architecture and signaling pathways.
