Analytical Data
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Gene name
CCDC88B
- Application
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Alternative Names
Brain leucine zipper domain containing Protein; Brain leucine zipper domain-containing Protein; Brain leucine zipper Protein; BRLZ; CC88B_HUMAN; CCDC 88; CCDC 88B; Ccdc88b; Coiled coil domain containing 88; Coiled coil domain containing Protein 88B
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A6NC98
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Expression Region
1-223aa
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AA Sequence
MRPWQAGSGGNSAQGSRWGEALSHSALGTPLGNDSDSAIQAPWGRPSPTAKDLVWDGRTPLRPCRNTKQMPTERALRYRNRRNVPSPHPSASDTVGTAGLGVQPSRHWSVSGGPRQPKSSGSQGPQGESLDKEAWALRSSTVSAGARRWSWDECVDRGDGWPPRAAPGWSSGSSRWLPLRQRSLGDPPAEGGWQELAREPPALSRWEAESQCWGTVAWADLEP
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Molecular Weight
50.5 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC88B (Coiled-Coil Domain Containing 88B) is a gene that encodes a protein involved in various cellular processes, including cytoskeletal organization, cell signaling, and immune response. Recent studies have highlighted its significance in the context of neurodevelopment and immunity. Mutations or dysregulation of CCDC88B have been implicated in several diseases, including neurodevelopmental disorders and autoimmune diseases, suggesting a crucial role in maintaining cellular homeostasis. The protein's coiled-coil domain suggests potential interactions with other proteins, indicating a role in forming complexes that facilitate cellular functions. Research into the recombinant expression of CCDC88B allows for the production of this protein in measurable quantities, enabling detailed functional assays and structural studies. By understanding the protein's interactions and functionalities, scientists aim to uncover its contributions to health and disease, potentially leading to novel therapeutic strategies targeting CCDC88B-related pathways. Thus, the study of CCDC88B recombinant protein represents a vital step in elucidating its biological roles and implications for human health.
