Analytical Data
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Gene name
RND2
- Application
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Alternative Names
ARHN; CTD-3199J23.4; GTP-binding protein Rho7; ras homolog gene family. member N; Rho 7; Rho family GTPase 2; Rho N; Rho related GTP-binding protein RhoN; Rho-related GTP-binding protein Rho7; Rho-related GTP-binding protein RhoN; Rho7; RhoN; Rnd 2; Rnd2; RND2_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P52198
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Expression Region
1-224 aa
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AA Sequence
MEGQSGRCKI VVVGDAECGK TALLQVFAKD AYPGSYVPTV FENYTASFEI DKRRIELNMW DTSGSSYYDN VRPLAYPDSD AVLICFDISR PETLDSVLKK WQGETQEFCP NAKVVLVGCK LDMRTDLATL RELSKQRLIP VTHEQGTVLA KQVGAVSYVE CSSRSSERSV RDVFHVATVA SLGRGHRQLR RTDSRRGMQR SAQLSGRPDR GNEGEIHKDR AKSC
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Molecular Weight
25.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RND2, a member of the Rho family of small GTPases, plays a crucial role in various cellular processes, including actin cytoskeleton organization, cell proliferation, and cell migration. Dysregulation of RND2 activity has been implicated in several diseases, including cancer, where it may influence tumor progression and metastasis. The study of RND2 recombinant proteins has gained significant interest as researchers aim to unravel the molecular mechanisms underlying its function. By producing RND2 in a laboratory setting, scientists can investigate its structural features, binding interactions, and downstream signaling pathways. Understanding the precise role of RND2 in cellular contexts is essential for developing targeted therapeutic strategies, particularly in oncology, where modulating its activity could lead to novel treatment approaches. The production and characterization of RND2 recombinant proteins allow for high-throughput screening of potential inhibitors or activators, contributing to the broader field of drug discovery and therapy for diseases linked to RND2 dysfunction. Ultimately, this research not only enhances our knowledge of RND2 biology but also paves the way for innovative interventions to combat diseases associated with its aberrant regulation.
