Analytical Data
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基因名
CCDC102B
- Application
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别名
ACY1L; aminoacylase 1-like1; AN; C102B_HUMAN; C18orf14; CCDC102B; chromosome 18 open reading frame 14; coiled-coil domain containing 102B; Coiled-coil domain-containing Protein 102B; DKFZp434K1426; DKFZp686I08254; FLJ23594; HsT1731; MGC161726; MGC161728
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q68D86
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表达区间
1-513aa
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氨基酸序列
MNLDSIHRLI EETQIFQMQQ SSIKSRGDMV APASPPRDTC NTCFPLHGLQ SHAAHNFCAH SYNTNKWDIC EELRLRELEE VKARAAQMEK TMRWWSDCTA NWREKWSKVR AERNSAREEG RQLRIKLEMA MKELSTLKKK QSLPPQKEAL EAKVTQDLKL PGFVEESCEH TDQFQLSSQM HESIREYLVK RQFSTKEDTN NKEQGVVIDS LKLSEEMKPN LDGVDLFNNG GSGNGETKTG LRLKAINLPL ENEVTEISAL QVHLDEFQKI LWKEREMRTA LEKEIERLES ALSLWKWKYE ELKESKPKNV KEFDILLGQH NDEMQELSGN IKEESKSQNS KDRVICELRA ELERLQAENT SEWDKREILE REKQGLEREN RRLKIQVKEM EELLDKKNRL SANSQSPDFK MSQIDLQEKN QELLNLQHAY YKLNRQYQAN IAELTHANNR VDQNEAEVKK LRLRVEELKQ GLNQKEDELD DSLNQIRKLQ RSLDEEKERN ENLETELRHL QNW
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分子量
60.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC102B, also known as Coiled-Coil Domain Containing 102B, is a protein that has garnered attention due to its potential roles in cellular processes and disease pathology. Recent studies have implicated mutations in the CCDC102B gene in the development of various neurodevelopmental disorders, particularly those associated with intellectual disability and autism spectrum disorders. Understanding the structure and function of CCDC102B is crucial for elucidating its biological significance and connection to these conditions. Researchers are increasingly focused on characterizing its interactions and pathways, as well as exploring its potential as a therapeutic target. The recombinant expression of CCDC102B allows scientists to investigate its molecular properties in detail, providing insights into its coiled-coil structure, which is typically involved in protein-protein interactions. By studying CCDC102B through recombinant techniques, researchers aim to reveal how alterations in this protein contribute to disease mechanisms. This knowledge could pave the way for the development of targeted interventions and improve our understanding of the genetic underpinnings of neurodevelopmental disorders. As the field advances, continued research on CCDC102B may unveil novel biological roles and therapeutic potentials that could benefit affected individuals and their families.
