Analytical Data
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Gene name
C4orf22
- Application
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Alternative Names
CFAP299; C4orf22Cilia- and flagella-associated Protein 299
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6V702
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Expression Region
1-233aa
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AA Sequence
MDQEEGLKALDNIVTQFNAYEDFLDSQITTVDLYYLEDETLARQLVELGYRGTGERVKREDFEARKAAIEIARLAERAQQKTLTSAGKDLQDNFLTALAMREEDNRSGKLSSVIFIRDRNSHGQEISGYIDYAHRLKTEDFEVYFTGKKRLLPRPTDISFYNWDADIAVSNSSPNYQVIADNPEGLLFRYKRDRKILNVDPKAQPGDNSTRITILTELYIQAVIFDHISRRKT
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Molecular Weight
53.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C4orf22, or Chromosome 4 Open Reading Frame 22, is a gene located on chromosome 4 that has garnered attention in recent years due to its potential roles in various biological processes, including neuronal functions and genetic regulation. Studies have indicated that mutations in the C4orf22 gene may be linked to certain diseases, notably those affecting neurological development, which has spurred research into its function and the protein it encodes. The recombinant C4orf22 protein has become a focal point for investigations aimed at understanding its structure, functional domains, and interactions with other cellular proteins. Researchers are particularly interested in how C4orf22 contributes to synaptic functions and neurological pathways, which may have implications for understanding disorders such as autism spectrum disorders and intellectual disabilities. Moreover, developing recombinant C4orf22 protein in various expression systems allows scientists to explore its biochemical properties, potential post-translational modifications, and cellular localization. By employing techniques such as immunohistochemistry and protein interaction assays, scientists aim to elucidate its role in cellular mechanisms and establish correlations between its function and associated pathologies. This increasing body of research reflects the broader interest in understudied gene products and their potential contributions to human health and disease. As investigations into C4orf22 progress, there is hope that findings will not only enhance our understanding of the protein's biological significance but also provide insights into novel therapeutic strategies for related neurological conditions.











