Cat: PA2000-2501

Recombinant mouse IFNT1 Protein,His

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Analytical Data

  • Gene name

    IFNT1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    IFNT1;Ifne1;Ifnt1;Interferon epsilon

  • Species

    Mouse

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q80ZF2

  • Expression Region

    1-192aa

  • AA Sequence

    MVHRQLPETVLLLLVSSTIFSLEPKRIPFQLWMNRESLQLLKPLPSSSVQQCLAHRKNFLLPQQPVSPHQYQEGQVLAVVHEILQQIFTLLQTHGTMGIWEENHIEKVLAALHRQLEYVESLGGLNAAQKSGGSSAQNLRLQIKAYFRRIHDYLENQRYSSCAWIIVQTEIHRCMFFVFRFTTWLSRQDPDP

  • Molecular Weight

    22.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

IFNT1 (Interferon Tau 1) is a type I interferon primarily produced by the conceptus during early pregnancy in ruminants, playing a crucial role in maternal recognition of pregnancy. Its function is pivotal in signaling the maternal system to prevent luteolysis, thereby sustaining progesterone production essential for embryo implantation and development. Research on IFNT1 has gained attention due to its potential applications in reproductive biotechnology, such as improving fertility in livestock and enhancing understanding of placentation mechanisms in mammals. Additionally, IFNT1 is involved in various immunomodulatory processes, making it a valuable subject in the study of immune responses during pregnancy. Recombinant production of IFNT1 enables detailed functional analyses, including its role in signaling pathways and interactions with other cytokines. Investigating IFNT1 at a molecular level facilitates the development of novel reproductive therapies and biotechnological advancements aimed at infertility treatment and effective breeding strategies in agriculture. This growing body of research underscores the significance of IFNT1 not only in reproductive biology but also in broader immunological contexts.

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