Analytical Data
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Gene name
C3orf17
- Application
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Alternative Names
NEPRO; C3orf17; Nucleolus and neural progenitor Protein
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6NW34
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Expression Region
1-567aa
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AA Sequence
MMAAVPPGLEPWNRVRIPKAGNRSAVTVQNPGAAIDLCIAAVIKECHLVILSLKSQTLDAETDVLCAVLYSNHNRMGRHKPHLALKQVEQCLKRLKNMNLEGSIQDLFELFSSNENQPLTTKVCVVPSQPVVELVLMKVLGACKLLLRLLDCCCKTFLLTVKHLGLQEFIILNLVMVGLVSRLWVLYKGVLKRLILLYEPLFGLLQEVARIQPMPYFKDFTFPSDITEFLGQPYFEAFKKKMPIAFAAKGINKLLNKLFLINEQSPRASEETLLGISKKAKQMKINVQNNVDLGQPVKNKRVFKEESSEFDVRAFCNQLKHKATQETSFDFKCSQSRLKTTKYSSQKVIGTPHAKSIVQRFREAESFTQLSEEIQMAVVWCRSKKLKAQAIFLGNKLLKSNRLKHLEAQGTSLPKKLECIKTSICNHLLRGSGIKTSKHHLRQRRSQNKFLRRQRKPQRKLQSTLLREIQQFSQGTRKSATDTSAKWRLSHCTVHRTDLYPNSKQLLNNGVSMPVIQTKGKMIHENLRGIHENETDSWTVMQINKNSTSGTIKETDDIDDIFALMGV
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Molecular Weight
90.9 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C3orf17, or Chromosome 3 Open Reading Frame 17, is a protein-coding gene located on chromosome 3, and its biological functions have attracted considerable interest in recent years due to its potential roles in various cellular processes. Studies have suggested that C3orf17 may be involved in cell proliferation, differentiation, and apoptosis, which are crucial for normal development and response to environmental stimuli. Dysregulation of this gene has been implicated in several diseases, including cancer, where it may contribute to tumorigenesis and metastasis. Furthermore, C3orf17 has been associated with inflammatory responses, indicating its relevance in autoimmune disorders. Research has focused on the structural characterization of C3orf17, including its protein domains and interactions with other cellular components. The generation of recombinant C3orf17 protein has facilitated investigations into its functional properties, enabling scientists to elucidate its mechanism of action and explore its potential as a therapeutic target. Understanding the biochemical pathways involving C3orf17 could provide insights into disease mechanisms and contribute to the development of novel diagnostic and therapeutic strategies. As research progresses, C3orf17 continues to emerge as a significant player in cellular biology, warranting further exploration to fully unravel its roles in health and disease.
