Analytical Data
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基因名
zipA
- Application
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别名
zipA；Cell division Protein ZipA
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种属
E.coli
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P77173
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表达区间
1-328aa
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氨基酸序列
MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRMKSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPRQPVQQPPEAQVPPQHAPHPAQPVQQPAYQPQPEQPLQQPVSPQVAPAPQPVHSAPQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA
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分子量
52.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of the ZipA protein, a key component of the divisome in bacterial cell division, has garnered significant attention in recent years due to its crucial role in facilitating cytokinesis in prokaryotic organisms. ZipA is an integral membrane protein that interacts with the FtsZ protein, which forms a ring-like structure at the site of cell division, providing a scaffold for other essential proteins involved in septum formation. Understanding the structure and function of ZipA is essential, as it not only helps elucidate the fundamental mechanisms of bacterial cell division but also presents potential targets for novel antibacterial therapies. As antibiotic resistance becomes an increasing global health concern, targeting bacterial cell division pathways, including those involving ZipA, offers a promising avenue for developing new drugs. Research often involves recombinant expression of ZipA, followed by biochemical and structural analyses, to determine its interaction mechanisms with FtsZ and other divisome components. Such studies are crucial for developing drugs that can effectively disrupt bacterial proliferation by targeting these essential proteins.
