Cat: PAX2000-10738

Recombinant Human RAI2 Protein,His

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Analytical Data

  • Gene name

    RAI2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    RAI2; Retinoic acid-induced protein 2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9Y5P3

  • Expression Region

    1-530 aa

  • AA Sequence

    MDDLQSQNLS MDMTDSPPAL ANNRLENGMA QLITTEAWNI NSTDLVKKAL VTVPAPSILN PPAESQSGMA LKVAATVLQP LCLGESPVVM PIHMQVEGSS APELNPNGNA TYVMTTQGPV QLPVVLEQHV FQHLNSPLVL PQEAPCSSST IHNNLFQGAE DPEAQPQLLD LRIPSQPQEP TLPFEAVLQN LFPSQGTLGP PPCQPPPGYA PVPPQPFSSP LSPLVPPATL LVPYPVIVPL PVPVPIPIPI PMPQSSESKF SSSFPKPPSS FGLHPFKGTQ TPLEKDELKP FDILQPKEYF QLSRHTVIKM GSENEALDLS MKSVPWLKAG EVSPPIFQED AALDLSVAAH RKSEPPPETL YDSGASVDSS GHTVMEKLPS GMEISFAPAT SHEAPAMMDS HISSSDAATE MLSQPNHPSG EVKAENNIEM VGESQAAKVI VSVEDAVPTI FCGKIKGLSG VSTKNFSFKR EDSVLQGYDI NSQGEESMGN AEPLRKPIKN RSIKLKKVNS QEIHMLPIKK QRLATFFPRK

  • Molecular Weight

    57.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

RAI2 (Regulator of Anti-viral Interferon Signaling 2) is a protein that plays a crucial role in the regulation of antiviral signaling pathways and immune responses. Initially identified for its potential involvement in interferon signaling, RAI2 has garnered attention in recent years due to its multifaceted roles in cell proliferation, apoptosis, and viral pathogenesis. Research has indicated that RAI2 can modulate the expression of various genes associated with immune responses, making it a significant factor in host defense mechanisms against viral infections. Moreover, studies have implicated RAI2 in the development of certain diseases, including cancer, by influencing cell cycle regulation and apoptosis. The understanding of RAI2's function in these processes has propelled the exploration of its potential as a therapeutic target or biomarker in various diseases. Recombinant RAI2 proteins are being studied to elucidate their structure-function relationships and mechanisms of action, paving the way for developing novel antiviral therapies and cancer treatments. The ongoing research endeavors aim to unravel the complexities of RAI2’s role in immune regulation and its potential applications in clinical settings, highlighting the importance of this protein in modern biomedical research.

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