Analytical Data
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基因名
RAB7L1
- Application
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别名
DKFZp686P1051; Rab 7 like protein 1; RAB 7L; Rab-7-like protein 1; RAB29; Rab7 like protein 1; RAB7 member RAS oncogene family like 1; RAB7L; RAB7L_HUMAN; Ras related protein Rab 7L1; Ras related protein Rab7L1; Ras-related protein Rab-29; Ras-related protein Rab-7L1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O14966
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表达区间
1-203 aa
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氨基酸序列
MGSRDHLFKV LVVGDAAVGK TSLVQRYSQD SFSKHYKSTV GVDFALKVLQ WSDYEIVRLQ LWDIAGQERF TSMTRLYYRD ASACVIMFDV TNATTFSNSQ RWKQDLDSKL TLPNGEPVPC LLLANKCDLS PWAVSRDQID RFSKENGFTG WTETSVKENK NINEAMRVLI EKMMRNSTED IMSLSTQGDY INLQTKSSSW SCC
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分子量
23.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB7L1 is a member of the RAB family of small GTPases, which play critical roles in intracellular vesicle trafficking, endosomal dynamics, and autophagy. Emerging research has highlighted RAB7L1's involvement in various cellular processes, particularly its influence on the late endosomal/lysosomal pathway. Studies have suggested that RAB7L1 may be implicated in neurodegenerative diseases and certain cancers due to its regulatory functions in membrane trafficking and degradation. Recombinant RAB7L1 proteins have been developed to facilitate in vitro studies, enabling researchers to investigate its GTPase activity, binding interactions, and role in cellular signaling pathways. These recombinant proteins also serve as valuable tools for high-throughput screening of potential therapeutic compounds targeting related pathways. Understanding RAB7L1's mechanisms could unveil new insights into cellular health and disease, highlighting its potential as a therapeutic target. With the advancement of protein engineering techniques, the production of RAB7L1 recombinant proteins continues to be a crucial area of research, contributing to the broader understanding of RAB GTPases in cell biology.
