Analytical Data
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Gene name
RAB7B
- Application
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Alternative Names
MGC16212; MGC9726; RAB7; rab7B; RAB7B; member RAS oncogene family ; RAB7B_HUMAN; Ras related protein Rab 7b; Ras-related protein Rab-7B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96AH8
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Expression Region
1-199 aa
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AA Sequence
MNPRKKVDLK LIIVGAIGVG KTSLLHQYVH KTFYEEYQTT LGASILSKII ILGDTTLKLQ IWDTGGQERF RSMVSTFYKG SDGCILAFDV TDLESFEALD IWRGDVLAKI VPMEQSYPMV LLGNKIDLAD RKVPQEVAQG WCREKDIPYF EVSAKNDINV VQAFEMLASR ALSRYQSILE NHLTESIKLS PDQSRSRCC
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Molecular Weight
22.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB7B, a member of the RAB family of small GTPases, plays a critical role in endosomal and lysosomal trafficking, which is essential for maintaining cellular homeostasis and signal transduction. Recent studies have highlighted its involvement in various cellular processes such as autophagy, neurotransmitter release, and immune response. Dysregulation of RAB7B has been implicated in several diseases, including neurodegenerative disorders and cancer, making it a potential biomarker and therapeutic target. The expression and functional analysis of recombinant RAB7B protein have garnered significant interest in the biotechnological and pharmaceutical fields. By producing RAB7B recombinantly, researchers can investigate its molecular mechanisms, interactions with other proteins, and role in disease pathology. Furthermore, understanding the structure-function relationship of RAB7B can facilitate the development of targeted therapies aimed at modulating its activity. Overall, the research surrounding recombinant RAB7B protein not only enhances our understanding of fundamental cellular processes but also opens avenues for innovative treatments in related diseases.
