Analytical Data
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基因名
CNTN3
- Application
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别名
CNTN3；KIAA1496；PANG；Contactin-3
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种属
Mouse
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q07409
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表达区间
1-1001aa
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氨基酸序列
MMLSWKQLIL LSFIGCLAGE LLLQGPVFIK EPSNSIFPVD SEDKKITLNC EARGNPSPHY RWQLNGSDID TSLDHRYKLN GGNLIVINPN RNWDTGSYQC FATNSLGTIV SREAKLQFAY LENFKTRMRS TVSVREGQGV VLLCGPPPHS GELSYAWVFN EYPSFVEEDS RRFVSQETGH LYIAKVEPSD VGNYTCVVTS TVTNTRVLGS PTPLVLRSDG VMGEYEPKIE VQFPETLPAA KGSTVRLECF ALGNPVPQIN WRRSDGMPFP NKIKLRKFNG MLEIQNFQQE DTGSYECIAE NSRGKNVARG RLTYYAKPYW LQLLRDVEIA VEDSLYWECR ASGKPKPSYR WLKNGDALVL EERIQIENGA LTITNLNVTD SGMFQCIAEN KHGLIYSSAE LKVVASAPDF SRNPMKKMVQ VQVGSLVILD CKPRASPRAL SFWKKGDMMV REQARVSFLN DGGLKIMNVT KADAGTYTCT AENQFGKANG TTHLVVTEPT RIILAPSNMD VAVGESVILP CQVQHDPLLD IMFAWYFNGA LTDFKKDGSH FEKVGGSSSG DLMIRNIQLK HSGKYVCMVQ TGVDSVSSAA ELIVRGSPGP PENVKVDEIT DTTAQLSWTE GTDSHSPVIS YAVQARTPFS VGWQSVRTVP EVIDGKTHTA TVVELNPWVE YEFRIVASNK IGGGEPSLPS EKVRTEEAAP EIAPSEVSGG GGSRSELVIT WDPVPEELQN GGGFGYVVAF RPLGVTTWIQ TVVTSPDNPR YVFRNESIVP FSPYEVKVGV YNNKGEGPFS PVTTVFSAEE EPTVAPSHIS AHSLSSSEIE VSWNTIPWKL SNGHLLGYEV RYWNNGGEEE SSRKVKVAGN QTSAVLRGLK SNLAYYTAVR AYNSAGAGPF SATVNATTKK TPPSQPPGNV VWNATDTKVL LNWEQVKAME NESEVTGYKV FYRTSSQNNV HVLNTNKTSA ELLLPIKEDY IIEVKATTDG GDGTSSEQIR IPRITSMDAR G
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分子量
110 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CNTN3, or Contactin-3, is a member of the contactin family of proteins, which are heavily involved in the development and maintenance of the nervous system. Research has indicated that CNTN3 plays a crucial role in neuronal cell adhesion, axon guidance, and myelination. Abnormal expression or mutations in the CNTN3 gene have been associated with various neurodevelopmental disorders, including autism spectrum disorders and cognitive disabilities, highlighting its importance in brain function and neural connectivity. The recombinant version of CNTN3 is of significant interest for researchers aiming to elucidate its biological functions, interactions with other proteins, and its potential role in disease mechanisms. By producing CNTN3 as a recombinant protein, scientists can investigate its structural properties, binding characteristics, and effects on neuronal cell behavior in vitro and in vivo. This research could pave the way for therapeutic strategies targeting CNTN3-related disorders, thereby advancing our understanding of the molecular underpinnings of neurodevelopmental conditions and facilitating the development of novel interventions or treatments. Through this foundational research on CNTN3 recombinant protein, insights into the complex dynamics of neuronal networks and their implications for health and disease may be gained, offering promising avenues for future biomedical applications.
