Analytical Data
-
Gene name
RAB4B
- Application
-
Alternative Names
1500031G17Rik; FLJ78649; MGC52123; OTTMUSP00000026157; RAB4B; RAB4B; member RAS oncogene family; RAB4B_HUMAN; Ras related GTP binding protein 4b; Ras related protein Rab 4B; Ras-related protein Rab-4B; Small GTP binding protein RAB4B
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P61018
-
Expression Region
1-213 aa
-
AA Sequence
MAETYDFLFK FLVIGSAGTG KSCLLHQFIE NKFKQDSNHT IGVEFGSRVV NVGGKTVKLQ IWDTAGQERF RSVTRSYYRG AAGALLVYDI TSRETYNSLA AWLTDARTLA SPNIVVILCG NKKDLDPERE VTFLEASRFA QENELMFLET SALTGENVEE AFLKCARTIL NKIDSGELDP ERMGSGIQYG DASLRQLRQP RSAQAVAPQP CGC
-
Molecular Weight
23.5 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB4B is a member of the RAS oncogene family and belongs to the RAB family of small GTPases, which play crucial roles in intracellular trafficking and membrane dynamics. Research on RAB4B has gained attention due to its involvement in various cellular processes such as endocytosis, exocytosis, and cytoskeletal dynamics. It is particularly noted for its role in the recycling of membrane proteins, which is essential for maintaining cellular homeostasis and regulating signaling pathways. Aberrant expression of RAB4B has been linked to several cancer types and diseases, highlighting its potential as a biomarker and therapeutic target. Moreover, the study of RAB4B recombinant proteins provides insights into its functional mechanisms and interactions with other cellular components. Advances in molecular biology techniques, such as recombinant DNA technology, have enabled the successful expression and purification of RAB4B. These studies are crucial for designing experiments that can elucidate the precise roles of RAB4B in health and disease, thereby contributing to our understanding of cancer biology and the development of targeted treatments. The exploration of RAB4B's structure and function through recombinant protein studies holds promise for future research aimed at novel therapeutic strategies.
