Analytical Data
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Gene name
RAB43
- Application
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Alternative Names
RAB41; RAB43; RAB43_HUMAN; Ras related protein Rab 41 ; Ras related protein Rab 43; Ras-related protein Rab-41; Ras-related protein Rab-43
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86YS6
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Expression Region
1-212 aa
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AA Sequence
MAGPGPGPGD PDEQYDFLFK LVLVGDASVG KTCVVQRFKT GAFSERQGST IGVDFTMKTL EIQGKRVKLQ IWDTAGQERF RTITQSYYRS ANGAILAYDI TKRSSFLSVP HWIEDVRKYA GSNIVQLLIG NKSDLSELRE VSLAEAQSLA EHYDILCAIE TSAKDSSNVE EAFLRVATEL IMRHGGPLFS EKSPDHIQLN SKDIGEGWGC GC
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Molecular Weight
23.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB43 is a member of the RAB GTPase family, which plays a crucial role in intracellular vesicle trafficking, membrane dynamics, and organelle communication. Recent studies have highlighted its significance in processes such as endocytosis and exocytosis, as well as its involvement in the transport of various cargo proteins and lipids within cells. Researchers have focused on understanding the molecular mechanisms by which RAB43 regulates vesicle trafficking pathways and its potential impact on cellular functions. Moreover, abnormal expression or mutations in RAB43 have been linked to various diseases, including neurological disorders and cancer, which raises the importance of studying its functions and interactions at both the cellular and molecular levels. The development of recombinant RAB43 proteins is pivotal for dissecting these biological roles, allowing scientists to investigate its structure, binding interactions with effector proteins, and its regulatory mechanisms in vesicle transport. Through this research, insights into the cellular processes governed by RAB43 could pave the way for novel therapeutic strategies targeting diseases associated with dysregulated vesicle trafficking.
