Cat: PAX2000-10697

Recombinant Human RAB42 Protein,His

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Analytical Data

  • 基因名

    RAB42

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    RAB42; Ras-related protein Rab-42

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q8N4Z0

  • 表达区间

    1-105 aa

  • 氨基酸序列

    MATQGPDKVI FLLVGHKSDL QSTRCVSAQE AEELAASLGM AFVETSVKNN CNVDLAFDTL ADAIQQALQQ GDIKLEEGWG GVRLIHKTQI PRSPSRKQHS GPCQC

  • 分子量

    24.1 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

RAB42 is a member of the RAB family of small GTPases, which are pivotal in regulating intracellular membrane trafficking and organelle dynamics. RAB proteins have gained attention due to their roles in various cellular processes including endocytosis, exocytosis, and the maintenance of organelle identity. Recent studies have implicated RAB42 in neurobiology and cancer, suggesting it may influence neuronal development and function, as well as playing a role in tumorigenesis. The unique expression patterns of RAB42 in different tissues highlight its potential as a biomarker and therapeutic target. Recombining RAB42 into a fusion protein can facilitate functional studies and elucidate its interactions with other proteins, thereby aiding in understanding its specific role in complex cellular pathways. Current research focuses on the functional characterization of RAB42, exploring its molecular mechanisms and effects on cellular physiology, as well as the potential implications of its dysregulation in disease. Advances in recombinant protein technology allow for the production of RAB42 in heterologous systems, enabling high-yield generation and purification for detailed structural and functional analyses. By shedding light on RAB42's biological functions, this research can contribute to a deeper understanding of its involvement in health and disease, paving the way for novel therapeutic strategies targeting RAB42-related pathways.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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