Analytical Data
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基因名
RAB11FIP3
- Application
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别名
RAB11FIP3; ARFO1; KIAA0665; Rab11 family-interacting protein 3; FIP3-Rab11; Rab11-FIP3; Arfophilin-1; EF hands-containing Rab-interacting protein; Eferin; MU-MB-17.148
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75154
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表达区间
1-756 aa
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氨基酸序列
MASAPPASPP GSEPPGPDPE PGGPDGPGAA QLAPGPAELR LGAPVGGPDP QSPGLDEPAP GAAADGGARW SAGPAPGLEG GPRDPGPSAP PPRSGPRGQL ASPDAPGPGP RSEAPLPELD PLFSWTEEPE ECGPASCPES APFRLQGSSS SHRARGEVDV FSPFPAPTAG ELALEQGPGS PPQPSDLSQT HPLPSEPVGS QEDGPRLRAV FDALDGDGDG FVRIEDFIQF ATVYGAEQVK DLTKYLDPSG LGVISFEDFY QGITAIRNGD PDGQCYGGVA SAQDEEPLAC PDEFDDFVTY EANEVTDSAY MGSESTYSEC ETFTDEDTST LVHPELQPEG DADSAGGSAV PSECLDAMEE PDHGALLLLP GRPHPHGQSV ITVIGGEEHF EDYGEGSEAE LSPETLCNGQ LGCSDPAFLT PSPTKRLSSK KVARYLHQSG ALTMEALEDP SPELMEGPEE DIADKVVFLE RRVLELEKDT AATGEQHSRL RQENLQLVHR ANALEEQLKE QELRACEMVL EETRRQKELL CKMEREKSIE IENLQTRLQQ LDEENSELRS CTPCLKANIE RLEEEKQKLL DEIESLTLRL SEEQENKRRM GDRLSHERHQ FQRDKEATQE LIEDLRKQLE HLQLLKLEAE QRRGRSSSMG LQEYHSRARE SELEQEVRRL KQDNRNLKEQ NEELNGQIIT LSIQGAKSLF STAFSESLAA EISSVSRDEL MEAIQKQEEI NFRLQDYIDR IIVAIMETNP SILEVK
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分子量
82.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB11FIP3, a member of the RAB11 family of proteins, plays a crucial role in intracellular trafficking and the regulation of membrane transport processes. Research on RAB11FIP3 has garnered significant attention due to its involvement in various cellular functions, including endosomal recycling, cytokinesis, and the assembly of polarized cellular structures. Given its pivotal role in maintaining cellular homeostasis, dysregulation of RAB11FIP3 has been implicated in various diseases, including cancer and neurodegenerative disorders. Understanding the molecular mechanisms of RAB11FIP3 functioning can provide insights into the pathways that govern cellular distribution and localization of cargo proteins. Recent studies have employed recombinant protein technology to produce RAB11FIP3 for structural and functional analyses, enabling researchers to elucidate its interactions with other proteins, lipids, and cellular membranes. This characterization is vital for identifying potential therapeutic targets and developing strategies to manipulate RAB11FIP3 activity in pathological conditions. Additionally, the reconstitution of RAB11FIP3 in vitro has facilitated the exploration of its role in membrane dynamics, advancing our understanding of how this protein contributes to vesicular transport and signaling pathways within cells. Overall, the study of RAB11FIP3 recombinant proteins holds promise for uncovering new insights into the complexity of cellular logistics and their implications in human health and disease.
