Analytical Data
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基因名
PTCHD1
- Application
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别名
9630036J22Rik; AI848149; FLJ30296; Gm387; MGC149798; Patched domain containing 1; Patched domain-containing protein 1; PTCHD1; PTHD1_HUMAN; RGD1564527; RP23-152D15.3
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96NR3
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表达区间
1-256 aa
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氨基酸序列
MLDQHHTDLILKLHAAVTKIQVPRPGFNYTFAHICILNNDKTCIVDDIVHVLEELKNARATNRTNFAITYPITHLKDGRAVYNGHQLGGVTVHSKDRVKSAEAIQLTYYLQSINSLNDMVAERWESSFCDTVRLFQKSNSKVKMYPYTSSSLREDFQKTSRVSERYLVTSLILVVTMAILCCSMQDCVRSKPWLGLLGLVTISLATLTAAGIINLTGGKYNSTFLGVPFVMLGNYYSSFFCFRLLVVLTRFLKGQE
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分子量
55.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTCHD1 (Patched Domain Containing 1) is a gene implicated in various biological processes, including neuronal development and cancer biology. Research has indicated that PTCHD1 plays a pivotal role in the hedgehog signaling pathway, which is essential for proper cellular communication and tissue patterning during embryonic development. Mutations or alterations in the expression of PTCHD1 have been associated with developmental disorders and certain malignancies, making it a significant focus of investigation in medical research. The production and study of recombinant PTCHD1 protein have become crucial for understanding its functional mechanisms and interactions within biological systems. This recombinant protein serves as a valuable tool for biochemical assays and offers insights into its effects on cellular pathways, potentially aiding in the development of therapeutic strategies for conditions linked to PTCHD1 dysregulation. By exploring the structural and functional properties of PTCHD1, researchers aim to elucidate its role in both normal physiology and disease processes, helping to bridge the gap between basic science and clinical applications.
