Analytical Data
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Gene name
PTCHD1
- Application
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Alternative Names
9630036J22Rik; AI848149; FLJ30296; Gm387; MGC149798; Patched domain containing 1; Patched domain-containing protein 1; PTCHD1; PTHD1_HUMAN; RGD1564527; RP23-152D15.3
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96NR3
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Expression Region
1-256 aa
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AA Sequence
MLDQHHTDLILKLHAAVTKIQVPRPGFNYTFAHICILNNDKTCIVDDIVHVLEELKNARATNRTNFAITYPITHLKDGRAVYNGHQLGGVTVHSKDRVKSAEAIQLTYYLQSINSLNDMVAERWESSFCDTVRLFQKSNSKVKMYPYTSSSLREDFQKTSRVSERYLVTSLILVVTMAILCCSMQDCVRSKPWLGLLGLVTISLATLTAAGIINLTGGKYNSTFLGVPFVMLGNYYSSFFCFRLLVVLTRFLKGQE
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Molecular Weight
55.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PTCHD1 (Patched Domain Containing 1) is a gene implicated in various biological processes, including neuronal development and cancer biology. Research has indicated that PTCHD1 plays a pivotal role in the hedgehog signaling pathway, which is essential for proper cellular communication and tissue patterning during embryonic development. Mutations or alterations in the expression of PTCHD1 have been associated with developmental disorders and certain malignancies, making it a significant focus of investigation in medical research. The production and study of recombinant PTCHD1 protein have become crucial for understanding its functional mechanisms and interactions within biological systems. This recombinant protein serves as a valuable tool for biochemical assays and offers insights into its effects on cellular pathways, potentially aiding in the development of therapeutic strategies for conditions linked to PTCHD1 dysregulation. By exploring the structural and functional properties of PTCHD1, researchers aim to elucidate its role in both normal physiology and disease processes, helping to bridge the gap between basic science and clinical applications.
