Analytical Data
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Gene name
C17orf70
- Application
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Alternative Names
C17orf70; chromosome 17 open reading frame 70; Faap100; Fanconi anemia associated Protein 100 kDa subunit; Fanconi anemia associated Protein 100kDa; Fanconi anemia core complex 100 kDa subunit; Fanconi anemia-associated Protein of 100 kDa; FP100_HUMAN
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q0VG06
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Expression Region
1-233aa
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AA Sequence
MLQCLRFPGLALPHTRAPSPLGPTRDPVATFLETCREPGSQPAGPASLRAEYLPPSVASIKVSAELLRAALKDGHSGVPLCCATLQWLLAENAAVDVVRARALSSIQGVAPDGANVHLIVREVAMTDLCPAGPIQAVEIQVESSSLADICRAHHAVVGRMQTMVTEQAAQGSSAPDLRVQYLRQIHANHETLLREVQTLRDRLCTEDEASSCATAQRLLQVYRQLRHPSLILL
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Molecular Weight
25.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C17orf70, located on chromosome 17, has garnered attention in recent years due to its potential roles in cellular processes and disease mechanisms. Initially classified as a gene with unknown function, studies have suggested its involvement in key biological pathways, including cell proliferation and apoptosis. Abnormal expression of C17orf70 has been linked to various cancers, prompting further investigation into its biological significance and molecular mechanisms. Recent advancements in proteomics and molecular biology techniques have facilitated the production of recombinant C17orf70 protein, enabling researchers to explore its structure, function, and interactions at a deeper level. This recombinant protein serves as a crucial tool for elucidating the role of C17orf70 in cancer biology and other cellular processes, providing insight into its potential as a therapeutic target. As research progresses, understanding C17orf70's role in health and disease could reveal novel strategies for diagnosis and treatment, highlighting the importance of this previously underexplored protein in biomedical research.
