Cat: PA2000-6046

Recombinant Human C17orf63 Protein,GST

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Analytical Data

  • Gene name

    C17orf63

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    FAM222B; C17orf63Protein FAM222B

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8WU58

  • Expression Region

    1-562aa

  • AA Sequence

    MLACLPGPGD LSFQLLSHTQ MNTGLQKWDT TQKMRTAHYP TPAELDAYAK KVANNPLTIK IFPNSVKVPQ RKHVRRTVNG LDTSAQRYSP YPTQAATKAG LLAIVKVPAK SILKDFDGTR ARLLPEAIMN PPVAPYATVA PSTLAHPQAQ ALARQQALQH AQTLAHAPPQ TLQHPQGIPP PQALSHPQSL QQPQGLGHPQ PMAQTQGLVH PQALAHQGLQ HPHNPLLHGG RKMPDSDAPP NVTVSTSTIP LSMAATLQHS QPPDLSSIVH QINQFCQTRA GISTTSVCEG QIANPSPISR SLLINASTRV STHSVPTPMP SCVVNPMEHT HAATAALPAA GPVNLPTGIS RVPTGYPSDL KPVTWNQHQL AHLQQMCSEA SGTPAPGLTG KHAAGRELAG PGFVGKAPAY PQELCLAQSF HLKPPLEKPT PSPPVNGMAA PLAYPNGHYF QPLWNNILPT PNSDSSGSQD LAMPFHGGQP TGAPLDCAAA PGAHYRAGTG GGPVASQNSL MQTVDYLSGD FQQACFREQS LAMLSKAHRA PGNRAPDPTE SRSLHIQHPG YR

  • Molecular Weight

    86.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

C17orf63, also known as TMSB4X, is a gene located on chromosome 17 that encodes a protein involved in various cellular processes, including cytoskeletal organization and cell signaling. The interest in studying C17orf63 recombinant protein arises from its potential implications in understanding cancer biology and other diseases. Preliminary research has suggested that alterations in the expression levels of C17orf63 may correlate with tumorigenesis and metastasis in various cancer types. Furthermore, the protein also plays a role in the modulation of immune responses, making it a candidate for investigations into autoimmune disorders and inflammatory conditions. The recombinant expression of C17orf63 allows researchers to produce large quantities of the protein for biochemical analysis and functional studies. Techniques such as bacterial expression systems or mammalian cell systems are often employed to obtain a properly folded and functional protein, which can then be used in assays to evaluate its biochemical properties, interactions with other cellular components, and effects on cellular functions. Understanding the role of C17orf63 in cellular activities could provide insights into its mechanisms and potential as a therapeutic target or biomarker. Expanding our knowledge about this protein could ultimately contribute to the development of novel diagnostic and therapeutic approaches for cancer and other diseases associated with its dysregulation. Thus, the study of C17orf63 recombinant protein is a promising avenue for expanding our understanding of complex biological systems and their implications in health and disease.

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