Analytical Data
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基因名
PRSS25
- Application
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别名
HTRA2; OMI; PRSS25; Serine protease HTRA2. mitochondrial; High temperature requirement protein A2; HtrA2; Omi stress-regulated endoprotease; Serine protease 25; Serine proteinase OMI
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O43464
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表达区间
134-458 aa
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氨基酸序列
MAVPSPPPASPPSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPISNGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNAGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAVRTQSQLAVQIRRGRETLTLYVTPEVTEGSHHHHHH
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分子量
36 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PRSS25, also known as trypsin-like serine protease, is a serine protease that plays a crucial role in various biological processes, including digestion, cell signaling, and immune responses. Its unique structure and function have drawn significant interest in the fields of biochemistry and molecular biology. PRSS25 is primarily expressed in the pancreas and is known to be involved in the activation of zymogens and the regulation of proteolytic enzymes. Furthermore, dysregulation or altered expression of PRSS25 has been implicated in various pathological conditions, including pancreatic diseases and certain cancers. Research efforts have focused on the recombinant expression of PRSS25 to better understand its enzymatic activity, substrate specificity, and potential therapeutic applications. The use of recombinant protein technology allows for the production of PRSS25 in heterologous systems, facilitating detailed biochemical characterization. By studying the structural and functional aspects of PRSS25, researchers aim to elucidate its role in physiological and pathological conditions, ultimately seeking to develop strategies for targeted therapies that leverage its proteolytic activity. The advancement of PRSS25 recombinant protein studies can provide insights into the underlying mechanisms of diseases and contribute to the development of diagnostic and therapeutic tools.
