Analytical Data
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Gene name
APCS
- Application
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Alternative Names
APCS；PTX2；Serum amyloid P-component
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P02743
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Expression Region
20-223aa
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AA Sequence
HTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYSDLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESSSGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWDSVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
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Molecular Weight
27.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The research on APCS (Acute Phase Protein Serum) recombinant proteins is rooted in the understanding of the immune response and inflammatory processes in the body. APCS is a member of the serum amyloid P component family, which plays a crucial role in the acute phase response to injury or infection. As a marker and mediator of inflammation, APCS is produced predominantly by the liver and is involved in various physiological functions, including modulation of immune responses, maintenance of homeostasis, and clearance of pathogens. The interest in recombinant forms of APCS arises from their potential applications in both research and clinical settings, including their use as diagnostic markers for diseases and therapeutic agents in inflammation-related disorders. Advancements in genetic engineering techniques have enabled the production of high-purity, biologically active recombinant APCS, which can facilitate in-depth studies into its structure-function relationships, biophysical properties, and interactions with other proteins. Moreover, understanding the role of APCS in pathologies such as sepsis, autoimmune diseases, and cancer positions it as a promising target for drug development, making the exploration of its recombinant forms vital for future biomedical advancements.
