Analytical Data
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Gene name
MUC15
- Application
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Alternative Names
MUC15；Mucin-15
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N387
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Expression Region
1-334aa
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AA Sequence
MLALAKILLISTLFYSLLSGSHGKENQDINTTQNIAEVFKTMENKPISLESEANLNSDKENITTSNLKASHSPPLNLPNNSHGITDFSSNSSAEHSLGSLKPTSTISTSPPLIHSFVSKVPWNAPIADEDLLPISAHPNATPALSSENFTWSLVNDTVKTPDNSSITVSILSSEPTSPSVTPLIVEPSGWLTTNSDSFTGFTPYQEKTTLQPTLKFTNNSKLFPNTSDPQKENRNTGIVFGAILGAILGVSLLTLVGYLLCGKRKTDSFSHRRLYDDRNEPVLRLDNAPEPYDVSFGNSSYYNPTLNDSAMPESEENARDGIPMDDIPPLRTSV
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MUC15, a member of the mucin family of glycoproteins, has garnered significant attention in recent years due to its potential role in various biological processes and diseases. Mucins are heavily glycosylated proteins primarily expressed in epithelial tissues, where they play critical roles in cell adhesion, pathogen defense, and the maintenance of epithelial integrity. MUC15 is particularly noteworthy for its expression in multiple tissues including the respiratory and gastrointestinal tracts, as well as in certain cancers. Studies have indicated that MUC15 may function as a tumor marker and might be involved in the modulation of immune responses. Its aberrant expression has been linked to tumorigenesis, making it a target of interest for cancer research. The investigation of recombinant MUC15 protein not only aims to clarify its biological functions but also to explore its potential applications in diagnostics and therapeutics. Through techniques such as recombinant DNA technology, researchers are working to produce MUC15 in a laboratory setting, allowing for comprehensive studies on its structure, function, and interactions with other biomolecules. Understanding the precise role of MUC15 in health and disease could pave the way for novel therapeutic strategies, highlighting the importance of ongoing research in this area.
