Cat: PA2000-5985

Recombinant Human C14orf45 Protein,GST

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Analytical Data

  • Gene name

    C14orf45

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    BBOF1; C14orf45; CCDC176Basal body-orientation factor 1; Coiled-coil domain-containing Protein 176

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8ND07

  • Expression Region

    1-228 aa

  • AA Sequence

    MTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRTEYPKIRTFDGREHSTNSVNQDLLEAEKWTHIEGNVDIGDLTWEQKEKVLRLLFAKMNGCPSRKYNQSSRPPVPDYVVSDSGETKEFGDESKLQDKIFITQQIAISDSSGEVVLPTIPKEPQESDTGTF

  • Molecular Weight

    52.7 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

C14orf45, a gene located on chromosome 14, has garnered increasing attention in recent years due to its potential roles in various biological processes and its implications in human diseases. Early studies suggested that C14orf45 might be involved in cellular functions such as apoptosis, cell proliferation, and immune response, which highlights its significance in maintaining cellular homeostasis. Furthermore, emerging evidence indicates that mutations or dysregulation of C14orf45 may be linked to certain cancers and neurodegenerative disorders. The exploration of C14orf45 recombinant protein has opened new avenues for understanding its functional mechanisms. By producing and characterizing recombinant C14orf45, researchers aim to elucidate its structure, interaction with other molecules, and the pathways it influences. This research not only contributes to the fundamental knowledge of C14orf45 but also holds promise for potential therapeutic interventions. As studies continue to unfold, C14orf45 may become a valuable biomarker or therapeutic target in the context of disease.

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