Analytical Data
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Gene name
RNASE1
- Application
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Alternative Names
RNASE1；RIB1；RNS1；Ribonuclease pancreatic
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P07998
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Expression Region
29-156aa
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AA Sequence
KE SRAKKFQRQH MDSDSSPSSS STYCNQMMRR RNMTQGRCKP VNTFVHEPLV DVQNVCFQEK VTCKNGQGNC YKSNSSMHIT DCRLTNGSRY PNCAYRTSPK ERHIIVACEG SPYVPVHFDA SVEDST
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RNASE1, a highly conserved ribonuclease, plays a significant role in various biological processes, including cellular differentiation, apoptosis, and immune responses. Research on RNASE1 has gained momentum due to its potential therapeutic applications, particularly in cancer treatment and antiviral therapy. Its enzymatic activity allows the degradation of RNA, which can inhibit the proliferation of certain pathogenic organisms and cancer cells. Additionally, RNASE1's ability to regulate RNA levels in cells highlights its importance in maintaining cellular homeostasis and response to stress. To harness the therapeutic potential of RNASE1, researchers have been focusing on the production of recombinant RNASE1, enabling detailed studies of its structure and function, as well as exploring its application in drug development. The recombinant form of the protein offers advantages such as increased yield and purity, facilitating experimental approaches to investigate its mechanism of action. Furthermore, engineering RNASE1 to enhance its enzymatic activity or alter its specificity can lead to new strategies for targeting RNA-dependent diseases. Overall, the study of recombinant RNASE1 is poised to advance our understanding of its biological functions and foster the development of novel therapeutic interventions.
