Analytical Data
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基因名
NANOS2
- Application
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别名
NANOS2；NOS2；Nanos homolog 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P60321
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表达区间
1-138aa
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氨基酸序列
MQLPPFDMWKDYFNLSQVVWALIASRGQRLETQEIEEPSPGPPLGQDQGLGAPGANGGLGTLCNFCKHNGESRHVYSSHQLKTPDGVVVCPILRHYVCPVCGATGDQAHTLKYCPLNGGQQSLYRRSGRNSAGRRVKR
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分子量
31.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NANOS2 is a crucial protein that plays a significant role in the regulation of germ cell development and maintenance. It is part of the NANOS family of proteins, which are conserved across various species and are essential for germ line specification during embryogenesis. NANOS2 functions primarily by inhibiting the translation of specific mRNAs, thereby influencing cell differentiation and fate decisions. Research into NANOS2 has garnered attention due to its implications in reproductive biology, as it is vital for the proper formation and preservation of primordial germ cells. Mutations or dysregulation of NANOS2 have been linked to infertility and developmental disorders. Furthermore, understanding the mechanisms of NANOS2 can provide insights into not only germ cell biology but also broader aspects of stem cell research and developmental genetics. By investigating the pathways and interactions involving NANOS2, researchers aim to elucidate its role in cell proliferation and differentiation, contributing to the advancement of knowledge in developmental biology and potential therapeutic applications. This area of study is vital for both basic science and clinical contexts, as it has the potential to inform strategies for addressing reproductive health issues and developmental anomalies.
