Cat: PAX2000-10543

Recombinant Human PRG1 Protein,His

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Analytical Data

  • Gene name

    PRG1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Chondroitin sulfate proteoglycan core protein; Cytolytic granule proteoglycan core protein; FLJ12930; gp600; Hematopoetic proteoglycan core protein; Mastocytoma proteoglycan core protein; MGC9289; OTTHUMP00000019716; P.PG; PG19 core protein; Pgsg; Platelet proteoglycan core protein; platelet proteoglycan protein core; PLATELET PROTEOGLYCAN PROTEIN CORE; PPG; PPG; PRG; PRG1; PROTEOGLYCAN 1; proteoglycan 1; secretory granule; Proteoglycan 10K core protein; Proteoglycan peptide core protein; PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE; secretory granule proteoglycan 1; Secretory granule proteoglycan core peptide; Secretory granule proteoglycan core protein; Serglycin; serglycin proteoglycan; Sgc; Srgn; SRGN_HUMAN

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P10124

  • Expression Region

    28-158 aa

  • AA Sequence

    YPT RRARYQWVRC NPDSNSANCL EEKGPMFELL PGESNKIPRL RTDLFPKTRI QDLNRIFPLS EDYSGSGFGS GSGSGSGSGS GFLTEMEQDY QLVDESDAFH DNLRSLDRNL PSDSQDLGQH GLEEDFML

  • Molecular Weight

    17.6 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

PRG1 (Proline-Rich GPR1-like protein 1) is a member of a family of proteins known for their roles in cellular signaling and regulation. Recent studies have highlighted PRG1's potential involvement in various physiological processes, including neurodevelopment, immune response, and cancer biology. Its proline-rich domains suggest interactions with a range of signaling molecules and may facilitate protein-protein interactions, which are crucial for cellular communication and function. As a result, researchers are increasingly focused on understanding the molecular mechanisms underlying PRG1's activity. This includes elucidating its structural properties, identifying binding partners, and delineating its pathways of action within different cellular contexts. Given the diverse roles of PRG1, investigating its functional implications could provide valuable insights into the pathogenesis of diseases and potentially reveal new therapeutic targets. The recombinant production of PRG1 is essential for these studies, as it allows for detailed in vitro analysis and characterization of the protein. Overall, PRG1 stands out as a significant protein in the landscape of molecular research, representing a promising avenue for exploration in both basic and applied sciences.

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