Cat: PA1000-4134

Recombinant Human FAM19A4 Protein,His

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Analytical Data

  • Gene name

    FAM19A4

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    FAM19A4;FAM19A4;;Chemokine-like Protein TAFA-4

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q96LR4

  • Expression Region

    36-140aa

  • AA Sequence

    SQHLR GHAGHHQIKQ GTCEVVAVHR CCNKNRIEER SQTVKCSCFP GQVAGTTRAQ PSCVEASIVI QKWWCHMNPC LEGEDCKVLP DYSGWSCSSG NKVKTTKVTR

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

FAM19A4, a member of the Family with Sequence Similarity 19 (FAM19) gene family, has garnered attention in recent years due to its potential roles in various biological processes, including cancer biology and inflammatory responses. The protein encoded by the FAM19A4 gene is believed to function as a signaling molecule, influencing cell proliferation, differentiation, and apoptosis. Research has indicated that FAM19A4 may be involved in multiple malignancies, including breast and lung cancers, where altered expression levels have been associated with tumor progression and poor prognosis. In addition, its expression patterns in various tissues reveal its potential importance in the central nervous system and other organ systems, suggesting it may play a role in neurodegenerative diseases as well. Recombinant FAM19A4 protein has been utilized in experimental settings to elucidate its precise biological functions and mechanisms of action. Studies involving this recombinant protein aim to provide insights into its signaling pathways, interactions with other proteins, and potential applications in therapeutic strategies. The investigation of FAM19A4 not only enhances the understanding of its fundamental biological roles but also holds promise for potential diagnostic and therapeutic innovations in cancer treatment and management. Understanding the functional implications of FAM19A4 will contribute to broader efforts in molecular biology and pharmacology, paving the way for new interventions targeting diseases associated with its dysregulation.

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